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The Synthetic Peptide LyeTx I mn∆K, Derived from Lycosa erythrognatha Spider Toxin, Is Active against Methicillin-Resistant Staphylococcus aureus (MRSA) In Vitro and In Vivo.
Vieira APGC, de Souza AN, Lima WG, Brito JCM, Simião DC, Gonçalves LVR, Cordeiro LPB, de Oliveira Scoaris D, Fernandes SOA, Resende JM, Bechinger B, Verly RM, de Lima ME. Vieira APGC, et al. Among authors: de lima me. Antibiotics (Basel). 2024 Mar 8;13(3):248. doi: 10.3390/antibiotics13030248. Antibiotics (Basel). 2024. PMID: 38534683 Free PMC article.
A short synthetic peptide, based on LyeTx I from Lycosa erythrognatha venom, shows potential to treat pneumonia caused by carbapenem-resistant Acinetobacter baumannii without detectable resistance.
Lima WG, Brito JCM, de Lima ME, Pizarro ACST, Vianna MAMM, de Paiva MC, de Assis DCS, Cardoso VN, Fernandes SOA. Lima WG, et al. Among authors: de assis dcs, de paiva mc, de lima me. J Antibiot (Tokyo). 2021 Jul;74(7):425-434. doi: 10.1038/s41429-021-00421-6. Epub 2021 May 10. J Antibiot (Tokyo). 2021. PMID: 33972716
Shortened derivatives from native antimicrobial peptide LyeTx I: In vitro and in vivo biological activity assessment.
Fuscaldi LL, de Avelar Júnior JT, Dos Santos DM, Boff D, de Oliveira VLS, Gomes KAGG, Cruz RC, de Oliveira PL, Magalhães PP, Cisalpino PS, Farias LM, de Souza-Fagundes EM, Delp J, Leist M, Resende JM, Amaral FA, Pimenta AMC, Fernandes SOA, Cardoso VN, de Lima ME. Fuscaldi LL, et al. Among authors: de oliveira vls, de souza fagundes em, de lima me, de avelar junior jt, de oliveira pl. Exp Biol Med (Maywood). 2021 Feb;246(4):414-425. doi: 10.1177/1535370220966963. Epub 2020 Nov 11. Exp Biol Med (Maywood). 2021. PMID: 33175610 Free PMC article.
Synthesis and antimicrobial evaluation of two peptide LyeTx I derivatives modified with the chelating agent HYNIC for radiolabeling with technetium-99m.
Fuscaldi LL, Dos Santos DM, Pinheiro NG, Araújo RS, de Barros AL, Resende JM, Fernandes SO, de Lima ME, Cardoso VN. Fuscaldi LL, et al. Among authors: de barros al, de lima me. J Venom Anim Toxins Incl Trop Dis. 2016 Apr 22;22:16. doi: 10.1186/s40409-016-0070-y. eCollection 2016. J Venom Anim Toxins Incl Trop Dis. 2016. PMID: 27110232 Free PMC article.
137 results