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Thiosemicarbazones and 4-thiazolidinones indole-based derivatives: Synthesis, evaluation of antiproliferative activity, cell death mechanisms and topoisomerase inhibition assay.
de Oliveira JF, Lima TS, Vendramini-Costa DB, de Lacerda Pedrosa SCB, Lafayette EA, da Silva RMF, de Almeida SMV, de Moura RO, Ruiz ALTG, de Carvalho JE, de Lima MDCA. de Oliveira JF, et al. Among authors: de almeida smv, de moura ro, lima ts, de lacerda pedrosa scb, de carvalho je, de lima mdca. Eur J Med Chem. 2017 Aug 18;136:305-314. doi: 10.1016/j.ejmech.2017.05.023. Epub 2017 May 8. Eur J Med Chem. 2017. PMID: 28505535
Synthesis and in vitro anticancer activity of new 2-thioxo-oxazolidin-4-one derivatives.
Campos JF, Pereira MC, de Sena WLB, de Barros Martins CG, de Oliveira JF, da Cruz Amorim CA, de Melo Rêgo MJB, da Rocha Pitta MG, de Lima MDCA, da Rocha Pitta MG, da Rocha Pitta I. Campos JF, et al. Among authors: de sena wlb, de melo rego mjb, de barros martins cg, de oliveira jf, de lima mdca. Pharmacol Rep. 2017 Aug;69(4):633-641. doi: 10.1016/j.pharep.2017.03.005. Epub 2017 Mar 18. Pharmacol Rep. 2017. PMID: 28511054
Synthesis of novel indole derivatives as promising DNA-binding agents and evaluation of antitumor and antitopoisomerase I activities.
Lafayette EA, de Almeida SMV, Cavalcanti Santos RV, de Oliveira JF, Amorim CADC, da Silva RMF, Pitta MGDR, Pitta IDR, de Moura RO, de Carvalho Júnior LB, de Melo Rêgo MJB, de Lima MDCA. Lafayette EA, et al. Among authors: de almeida smv, de moura ro, de carvalho junior lb, de melo rego mjb, de oliveira jf, de lima mdca. Eur J Med Chem. 2017 Aug 18;136:511-522. doi: 10.1016/j.ejmech.2017.05.012. Epub 2017 May 4. Eur J Med Chem. 2017. PMID: 28531811
New 1,3-benzodioxole derivatives: Synthesis, evaluation of in vitro schistosomicidal activity and ultrastructural analysis.
Mariz Gomes da Silva LM, de Oliveira JF, Silva WL, da Silva AL, de Almeida Junior ASA, Barbosa Dos Santos VH, Alves LC, Brayner Dos Santos FA, Costa VMA, Aires AL, de Lima MDCA, Albuquerque MCPA. Mariz Gomes da Silva LM, et al. Among authors: de almeida junior asa, de oliveira jf, de lima mdca. Chem Biol Interact. 2018 Mar 1;283:20-29. doi: 10.1016/j.cbi.2018.01.016. Epub 2018 Jan 31. Chem Biol Interact. 2018. PMID: 29366735 Free article.
Novel indol-3-yl-thiosemicarbazone derivatives: Obtaining, evaluation of in vitro leishmanicidal activity and ultrastructural studies.
da Silva PR, de Oliveira JF, da Silva AL, Queiroz CM, Feitosa APS, Duarte DMFA, da Silva AC, de Castro MCAB, Pereira VRA, da Silva RMF, Alves LC, Dos Santos FAB, de Lima MDCA. da Silva PR, et al. Among authors: de lima mdca. Chem Biol Interact. 2020 Jan 5;315:108899. doi: 10.1016/j.cbi.2019.108899. Epub 2019 Nov 15. Chem Biol Interact. 2020. PMID: 31738906
Thiophene-thiosemicarbazone derivative (L10) exerts antifungal activity mediated by oxidative stress and apoptosis in C. albicans.
de Araújo Neto LN, de Lima MDCA, de Oliveira JF, de Souza ER, Feitosa Machado SE, de Souza Lima GM, Silva Buonafina MD, Brayner FA, Alves LC, Sandes JM, da Silva MV, de Castro MCAB, Pereira Neves R, Bezerra Mendonça-Junior FJ. de Araújo Neto LN, et al. Among authors: de lima mdca. Chem Biol Interact. 2020 Apr 1;320:109028. doi: 10.1016/j.cbi.2020.109028. Epub 2020 Feb 28. Chem Biol Interact. 2020. PMID: 32119865 Free article.
COVID-19 therapy: What weapons do we bring into battle?
de Almeida SMV, Santos Soares JC, Dos Santos KL, Alves JEF, Ribeiro AG, Jacob ÍTT, da Silva Ferreira CJ, Dos Santos JC, de Oliveira JF, de Carvalho Junior LB, de Lima MDCA. de Almeida SMV, et al. Among authors: de lima mdca. Bioorg Med Chem. 2020 Dec 1;28(23):115757. doi: 10.1016/j.bmc.2020.115757. Epub 2020 Sep 10. Bioorg Med Chem. 2020. PMID: 32992245 Free PMC article.
ACW-02 an Acridine Triazolidine Derivative Presents Antileishmanial Activity Mediated by DNA Interaction and Immunomodulation.
Albino SL, da Silva Moura WC, Reis MMLD, Sousa GLS, da Silva PR, de Oliveira MGC, Borges TKDS, Albuquerque LFF, de Almeida SMV, de Lima MDCA, Kuckelhaus SAS, Nascimento IJDS, Junior FJBM, da Silva TG, de Moura RO. Albino SL, et al. Among authors: de lima mdca. Pharmaceuticals (Basel). 2023 Jan 29;16(2):204. doi: 10.3390/ph16020204. Pharmaceuticals (Basel). 2023. PMID: 37259353 Free PMC article.
19 results