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Preclinical Investigation in Neuroprotective Effects of the GPR55 Ligand VCE-006.1 in Experimental Models of Parkinson's Disease and Amyotrophic Lateral Sclerosis.
Burgaz S, García C, Gonzalo-Consuegra C, Gómez-Almería M, Ruiz-Pino F, Unciti JD, Gómez-Cañas M, Alcalde J, Morales P, Jagerovic N, Rodríguez-Cueto C, de Lago E, Muñoz E, Fernández-Ruiz J. Burgaz S, et al. Among authors: de lago e. Molecules. 2021 Dec 16;26(24):7643. doi: 10.3390/molecules26247643. Molecules. 2021. PMID: 34946726 Free PMC article.
UCM707, an inhibitor of the anandamide uptake, behaves as a symptom control agent in models of Huntington's disease and multiple sclerosis, but fails to delay/arrest the progression of different motor-related disorders.
de Lago E, Fernández-Ruiz J, Ortega-Gutiérrez S, Cabranes A, Pryce G, Baker D, López-Rodríguez M, Ramos JA. de Lago E, et al. Eur Neuropsychopharmacol. 2006 Jan;16(1):7-18. doi: 10.1016/j.euroneuro.2005.06.001. Epub 2005 Jul 11. Eur Neuropsychopharmacol. 2006. PMID: 16006105
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