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Page 1
Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.
Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ. Baar MP, et al. Among authors: de keizer plj. Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031. Cell. 2017. PMID: 28340339 Free PMC article.
p53: Pro-aging or pro-longevity?
de Keizer PL, Laberge RM, Campisi J. de Keizer PL, et al. Aging (Albany NY). 2010 Jul;2(7):377-9. doi: 10.18632/aging.100178. Aging (Albany NY). 2010. PMID: 20657035 Free PMC article. No abstract available.
Targeted inhibition of metastatic melanoma through interference with Pin1-FOXM1 signaling.
Kruiswijk F, Hasenfuss SC, Sivapatham R, Baar MP, Putavet D, Naipal KA, van den Broek NJ, Kruit W, van der Spek PJ, van Gent DC, Brenkman AB, Campisi J, Burgering BM, Hoeijmakers JH, de Keizer PL. Kruiswijk F, et al. Oncogene. 2016 Apr 28;35(17):2166-77. doi: 10.1038/onc.2015.282. Epub 2015 Aug 17. Oncogene. 2016. PMID: 26279295 Free PMC article.
Maintenance and repair of an aging life cycle.
Baar MP, Van Willigenburg H, de Keizer PLJ. Baar MP, et al. Among authors: de keizer plj. Oncotarget. 2017 May 21;8(50):86985-86986. doi: 10.18632/oncotarget.18046. eCollection 2017 Oct 20. Oncotarget. 2017. PMID: 29152057 Free PMC article. No abstract available.
Senescent Cells Drive Frailty through Systemic Signals.
Lehmann J, Baar MP, de Keizer PLJ. Lehmann J, et al. Among authors: de keizer plj. Trends Mol Med. 2018 Nov;24(11):917-918. doi: 10.1016/j.molmed.2018.09.003. Epub 2018 Oct 3. Trends Mol Med. 2018. PMID: 30292430
ARDD 2020: from aging mechanisms to interventions.
Mkrtchyan GV, Abdelmohsen K, Andreux P, Bagdonaite I, Barzilai N, Brunak S, Cabreiro F, de Cabo R, Campisi J, Cuervo AM, Demaria M, Ewald CY, Fang EF, Faragher R, Ferrucci L, Freund A, Silva-García CG, Georgievskaya A, Gladyshev VN, Glass DJ, Gorbunova V, de Grey A, He WW, Hoeijmakers J, Hoffmann E, Horvath S, Houtkooper RH, Jensen MK, Jensen MB, Kane A, Kassem M, de Keizer P, Kennedy B, Karsenty G, Lamming DW, Lee KF, MacAulay N, Mamoshina P, Mellon J, Molenaars M, Moskalev A, Mund A, Niedernhofer L, Osborne B, Pak HH, Parkhitko A, Raimundo N, Rando TA, Rasmussen LJ, Reis C, Riedel CG, Franco-Romero A, Schumacher B, Sinclair DA, Suh Y, Taub PR, Toiber D, Treebak JT, Valenzano DR, Verdin E, Vijg J, Young S, Zhang L, Bakula D, Zhavoronkov A, Scheibye-Knudsen M. Mkrtchyan GV, et al. Aging (Albany NY). 2020 Dec 30;12(24):24484-24503. doi: 10.18632/aging.202454. Epub 2020 Dec 30. Aging (Albany NY). 2020. PMID: 33378272 Free PMC article. Review.
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