de Jonghe S - Search Results

1

Bicyclic α-Iminophosphonates as High Affinity Imidazoline I₂ Receptor Ligands for Alzheimer's Disease.

Abás S, Rodríguez-Arévalo S, Bagán A, Griñán-Ferré C, Vasilopoulou F, Brocos-Mosquera I, Muguruza C, Pérez B, Molins E, Luque FJ, Pérez-Lozano P, de Jonghe S, Daelemans D, Naesens L, Brea J, Loza MI, Hernández-Hernández E, García-Sevilla JA, García-Fuster MJ, Radan M, Djikic T, Nikolic K, Pallàs M, Callado LF, Escolano C. Abás S, et al. Among authors: de jonghe s. J Med Chem. 2020 Apr 9;63(7):3610-3633. doi: 10.1021/acs.jmedchem.9b02080. Epub 2020 Mar 19. J Med Chem. 2020. PMID: 32150414

2

Anti-SARS-CoV-2 Activity and Cytotoxicity of Amaryllidaceae Alkaloids from Hymenocallis littoralis.

Le NT, De Jonghe S, Erven K, Vermeyen T, Baldé AM, Herrebout WA, Neyts J, Pannecouque C, Pieters L, Tuenter E. Le NT, et al. Among authors: de jonghe s. Molecules. 2023 Apr 4;28(7):3222. doi: 10.3390/molecules28073222. Molecules. 2023. PMID: 37049986 Free PMC article.

3

Azapeptide activity-based probes for the SARS-CoV-2 main protease enable visualization of inhibition in infected cells.

Vanhoutte R, Barniol-Xicota M, Chiu W, Vangeel L, Jochmans D, De Jonghe S, Zidane H, Barr HM, London N, Neyts J, Verhelst SHL. Vanhoutte R, et al. Among authors: de jonghe s. Chem Sci. 2023 Jan 6;14(7):1666-1672. doi: 10.1039/d2sc04147b. eCollection 2023 Feb 15. Chem Sci. 2023. PMID: 36819852 Free PMC article.

4

Development of a robust and convenient dual-reporter high-throughput screening assay for SARS-CoV-2 antiviral drug discovery.

Chiu W, Schepers J, Francken T, Vangeel L, Abbasi K, Jochmans D, De Jonghe S, Thibaut HJ, Thiel V, Neyts J, Laporte M, Leyssen P. Chiu W, et al. Among authors: de jonghe s. Antiviral Res. 2023 Feb;210:105506. doi: 10.1016/j.antiviral.2022.105506. Epub 2022 Dec 21. Antiviral Res. 2023. PMID: 36565756 Free PMC article.

5

The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor In Vitro and Confer Resistance To Nirmatrelvir.

Jochmans D, Liu C, Donckers K, Stoycheva A, Boland S, Stevens SK, De Vita C, Vanmechelen B, Maes P, Trüeb B, Ebert N, Thiel V, De Jonghe S, Vangeel L, Bardiot D, Jekle A, Blatt LM, Beigelman L, Symons JA, Raboisson P, Chaltin P, Marchand A, Neyts J, Deval J, Vandyck K. Jochmans D, et al. Among authors: de vita c, de jonghe s. mBio. 2023 Feb 28;14(1):e0281522. doi: 10.1128/mbio.02815-22. Epub 2023 Jan 10. mBio. 2023. PMID: 36625640 Free PMC article.

6

Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3H)-Ones with Antiproliferative Activities.

Karelou M, Kampasis D, Kalampaliki AD, Persoons L, Krämer A, Schols D, Knapp S, De Jonghe S, Kostakis IK. Karelou M, et al. Among authors: de jonghe s. Molecules. 2023 Dec 2;28(23):7912. doi: 10.3390/molecules28237912. Molecules. 2023. PMID: 38067641 Free PMC article.

7

Identification of Z-Tyr-Ala-CHN₂, a Cathepsin L Inhibitor with Broad-Spectrum Cell-Specific Activity against Coronaviruses, including SARS-CoV-2.

Doijen J, Temmerman K, Van den Eynde C, Diels A, Van den Broeck N, Van Gool M, Heo I, Jaensch S, Zwaagstra M, Diosa Toro M, Chiu W, De Jonghe S, Leyssen P, Bojkova D, Ciesek S, Cinatl J, Verschueren L, Buyck C, Van Kuppeveld F, Neyts J, Van Loock M, Van Damme E. Doijen J, et al. Among authors: de jonghe s. Microorganisms. 2023 Mar 10;11(3):717. doi: 10.3390/microorganisms11030717. Microorganisms. 2023. PMID: 36985290 Free PMC article.

8

Photo-induced scandium-catalyzed biomimetic skeleton conversion of lathyrane to naturally rare eupholathone Euphorbia diterpenes.

Xu JB, Wen P, Wang N, Li X, Li JH, De Jonghe S, Schols D, Chen FZ, Gao F. Xu JB, et al. Among authors: de jonghe s. Chem Commun (Camb). 2023 Oct 12;59(82):12290-12293. doi: 10.1039/d3cc03541g. Chem Commun (Camb). 2023. PMID: 37752884

9

Visible-Light-Promoted Tandem Thiol-Ene Click Reaction/Transannular Cyclization and Regioselective Cyclopropane Ring-Opening to Construct Sulfur-Containing Euphorbia Diterpenes.

Wang N, Wang H, Wan LX, Li XH, Zhou XL, Li JH, De Jonghe S, Schols D, Xu JB, Gao F. Wang N, et al. Among authors: de jonghe s. Org Lett. 2023 Feb 3;25(4):597-602. doi: 10.1021/acs.orglett.2c04116. Epub 2023 Jan 20. Org Lett. 2023. PMID: 36662155

10

Synthesis, immunosuppressive activity and structure-activity relationship study of a new series of 4-N-piperazinyl-thieno[2,3-d]pyrimidine analogues.

Jang MY, De Jonghe S, Van Belle K, Louat T, Waer M, Herdewijn P. Jang MY, et al. Among authors: de jonghe s. Bioorg Med Chem Lett. 2010 Feb 1;20(3):844-7. doi: 10.1016/j.bmcl.2009.12.098. Epub 2010 Jan 4. Bioorg Med Chem Lett. 2010. PMID: 20064721

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