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The ion channel TRPV1 regulates the activation and proinflammatory properties of CD4⁺ T cells.
Bertin S, Aoki-Nonaka Y, de Jong PR, Nohara LL, Xu H, Stanwood SR, Srikanth S, Lee J, To K, Abramson L, Yu T, Han T, Touma R, Li X, González-Navajas JM, Herdman S, Corr M, Fu G, Dong H, Gwack Y, Franco A, Jefferies WA, Raz E. Bertin S, et al. Among authors: de jong pr. Nat Immunol. 2014 Nov;15(11):1055-1063. doi: 10.1038/ni.3009. Epub 2014 Oct 5. Nat Immunol. 2014. PMID: 25282159 Free PMC article.
The TRPA1 ion channel is expressed in CD4+ T cells and restrains T-cell-mediated colitis through inhibition of TRPV1.
Bertin S, Aoki-Nonaka Y, Lee J, de Jong PR, Kim P, Han T, Yu T, To K, Takahashi N, Boland BS, Chang JT, Ho SB, Herdman S, Corr M, Franco A, Sharma S, Dong H, Akopian AN, Raz E. Bertin S, et al. Among authors: de jong pr. Gut. 2017 Sep;66(9):1584-1596. doi: 10.1136/gutjnl-2015-310710. Epub 2016 Jun 20. Gut. 2017. PMID: 27325418 Free PMC article.
Novel immune function for the TRPV1 channel in T lymphocytes.
Bertin S, de Jong PR, Jefferies WA, Raz E. Bertin S, et al. Among authors: de jong pr. Channels (Austin). 2014;8(6):479-80. doi: 10.4161/19336950.2014.991640. Channels (Austin). 2014. PMID: 25530461 Free PMC article. No abstract available.
TRPV1: Turning up the heat on intestinal tumorigenesis.
de Jong PR, Bertin S, Raz E. de Jong PR, et al. Mol Cell Oncol. 2014 Dec 1;2(1):e975619. doi: 10.4161/23723556.2014.975619. eCollection 2015 Jan-Mar. Mol Cell Oncol. 2014. PMID: 27308393 Free PMC article.
A gp130-Src-YAP module links inflammation to epithelial regeneration.
Taniguchi K, Wu LW, Grivennikov SI, de Jong PR, Lian I, Yu FX, Wang K, Ho SB, Boland BS, Chang JT, Sandborn WJ, Hardiman G, Raz E, Maehara Y, Yoshimura A, Zucman-Rossi J, Guan KL, Karin M. Taniguchi K, et al. Among authors: de jong pr. Nature. 2015 Mar 5;519(7541):57-62. doi: 10.1038/nature14228. Epub 2015 Feb 25. Nature. 2015. PMID: 25731159 Free PMC article.
STAT3: An Anti-Invasive Factor in Colorectal Cancer?
de Jong PR, Mo JH, Harris AR, Lee J, Raz E. de Jong PR, et al. Cancers (Basel). 2014 Jul 3;6(3):1394-407. doi: 10.3390/cancers6031394. Cancers (Basel). 2014. PMID: 24995503 Free PMC article.
32 results