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Evolutionarily conserved regulators of tau identify targets for new therapies.
Kim J, de Haro M, Al-Ramahi I, Garaicoechea LL, Jeong HH, Sonn JY, Tadros B, Liu Z, Botas J, Zoghbi HY. Kim J, et al. Among authors: de haro m. Neuron. 2023 Mar 15;111(6):824-838.e7. doi: 10.1016/j.neuron.2022.12.012. Epub 2023 Jan 6. Neuron. 2023. PMID: 36610398 Free article.
Reduction of Nuak1 Decreases Tau and Reverses Phenotypes in a Tauopathy Mouse Model.
Lasagna-Reeves CA, de Haro M, Hao S, Park J, Rousseaux MW, Al-Ramahi I, Jafar-Nejad P, Vilanova-Velez L, See L, De Maio A, Nitschke L, Wu Z, Troncoso JC, Westbrook TF, Tang J, Botas J, Zoghbi HY. Lasagna-Reeves CA, et al. Among authors: de maio a, de haro m. Neuron. 2016 Oct 19;92(2):407-418. doi: 10.1016/j.neuron.2016.09.022. Epub 2016 Oct 6. Neuron. 2016. PMID: 27720485 Free PMC article.
TRIM28 regulates the nuclear accumulation and toxicity of both alpha-synuclein and tau.
Rousseaux MW, de Haro M, Lasagna-Reeves CA, De Maio A, Park J, Jafar-Nejad P, Al-Ramahi I, Sharma A, See L, Lu N, Vilanova-Velez L, Klisch TJ, Westbrook TF, Troncoso JC, Botas J, Zoghbi HY. Rousseaux MW, et al. Among authors: de maio a, de haro m. Elife. 2016 Oct 25;5:e19809. doi: 10.7554/eLife.19809. Elife. 2016. PMID: 27779468 Free PMC article.
High-Throughput Functional Analysis Distinguishes Pathogenic, Nonpathogenic, and Compensatory Transcriptional Changes in Neurodegeneration.
Al-Ramahi I, Lu B, Di Paola S, Pang K, de Haro M, Peluso I, Gallego-Flores T, Malik NT, Erikson K, Bleiberg BA, Avalos M, Fan G, Rivers LE, Laitman AM, Diaz-García JR, Hild M, Palacino J, Liu Z, Medina DL, Botas J. Al-Ramahi I, et al. Among authors: de haro m. Cell Syst. 2018 Jul 25;7(1):28-40.e4. doi: 10.1016/j.cels.2018.05.010. Epub 2018 Jun 20. Cell Syst. 2018. PMID: 29936182 Free PMC article.
35 results