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Phosphoproteomics of patient-derived xenografts identifies targets and markers associated with sensitivity and resistance to EGFR blockade in colorectal cancer.
Beekhof R, Bertotti A, Böttger F, Vurchio V, Cottino F, Zanella ER, Migliardi G, Viviani M, Grassi E, Lupo B, Henneman AA, Knol JC, Pham TV, de Goeij-de Haas R, Piersma SR, Labots M, Verheul HMW, Trusolino L, Jimenez CR. Beekhof R, et al. Among authors: de goeij de haas r. Sci Transl Med. 2023 Aug 16;15(709):eabm3687. doi: 10.1126/scitranslmed.abm3687. Epub 2023 Aug 16. Sci Transl Med. 2023. PMID: 37585503 Free article.
Quantifying exosome secretion from single cells reveals a modulatory role for GPCR signaling.
Verweij FJ, Bebelman MP, Jimenez CR, Garcia-Vallejo JJ, Janssen H, Neefjes J, Knol JC, de Goeij-de Haas R, Piersma SR, Baglio SR, Verhage M, Middeldorp JM, Zomer A, van Rheenen J, Coppolino MG, Hurbain I, Raposo G, Smit MJ, Toonen RFG, van Niel G, Pegtel DM. Verweij FJ, et al. J Cell Biol. 2018 Mar 5;217(3):1129-1142. doi: 10.1083/jcb.201703206. Epub 2018 Jan 16. J Cell Biol. 2018. PMID: 29339438 Free PMC article.
Kinase Inhibitor Treatment of Patients with Advanced Cancer Results in High Tumor Drug Concentrations and in Specific Alterations of the Tumor Phosphoproteome.
Labots M, Pham TV, Honeywell RJ, Knol JC, Beekhof R, de Goeij-de Haas R, Dekker H, Neerincx M, Piersma SR, van der Mijn JC, van der Peet DL, Meijerink MR, Peters GJ, van Grieken NCT, Jiménez CR, Verheul HMW. Labots M, et al. Cancers (Basel). 2020 Feb 1;12(2):330. doi: 10.3390/cancers12020330. Cancers (Basel). 2020. PMID: 32024067 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 33451764
Time dependent effect of cold ischemia on the phosphoproteome and protein kinase activity in fresh-frozen colorectal cancer tissue obtained from patients.
Buffart TE, van den Oord RAHM, van den Berg A, Hilhorst R, Bastiaensen N, Pruijt HFM, van den Brule A, Nooijen P, Labots M, de Goeij-de Haas RR, Dekker H, Piersma SR, Pham TV, van der Leij T, de Wijn R, Ruijtenbeek R, Jiménez CR, Verheul HMW. Buffart TE, et al. Clin Proteomics. 2021 Feb 18;18(1):8. doi: 10.1186/s12014-020-09306-6. Clin Proteomics. 2021. PMID: 33602116 Free PMC article.
Tumor Drug Concentration and Phosphoproteomic Profiles After Two Weeks of Treatment With Sunitinib in Patients with Newly Diagnosed Glioblastoma.
van Linde ME, Labots M, Brahm CG, Hovinga KE, De Witt Hamer PC, Honeywell RJ, de Goeij-de Haas R, Henneman AA, Knol JC, Peters GJ, Dekker H, Piersma SR, Pham TV, Vandertop WP, Jiménez CR, Verheul HMW. van Linde ME, et al. Clin Cancer Res. 2022 Apr 14;28(8):1595-1602. doi: 10.1158/1078-0432.CCR-21-1933. Clin Cancer Res. 2022. PMID: 35165100 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 35191463
20 results