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Overcoming adaptive resistance to anti-VEGF therapy by targeting CD5L.
LaFargue CJ, Amero P, Noh K, Mangala LS, Wen Y, Bayraktar E, Umamaheswaran S, Stur E, Dasari SK, Ivan C, Pradeep S, Yoo W, Lu C, Jennings NB, Vathipadiekal V, Hu W, Chelariu-Raicu A, Ku Z, Deng H, Xiong W, Choi HJ, Hu M, Kiyama T, Mao CA, Ali-Fehmi R, Birrer MJ, Liu J, Zhang N, Lopez-Berestein G, de Franciscis V, An Z, Sood AK. LaFargue CJ, et al. Among authors: de franciscis v. Nat Commun. 2023 Apr 26;14(1):2407. doi: 10.1038/s41467-023-36910-5. Nat Commun. 2023. PMID: 37100807 Free PMC article.
Targeted systematic evolution of an RNA platform neutralizing DNMT1 function and controlling DNA methylation.
Esposito CL, Autiero I, Sandomenico A, Li H, Bassal MA, Ibba ML, Wang D, Rinaldi L, Ummarino S, Gaggi G, Borchiellini M, Swiderski P, Ruvo M, Catuogno S, Ebralidze AK, Kortylewski M, de Franciscis V, Di Ruscio A. Esposito CL, et al. Among authors: de franciscis v. Nat Commun. 2023 Jan 6;14(1):99. doi: 10.1038/s41467-022-35222-4. Nat Commun. 2023. PMID: 36609400 Free PMC article.
Structure- and Interaction-Based Design of Anti-SARS-CoV-2 Aptamers.
Mironov V, Shchugoreva IA, Artyushenko PV, Morozov D, Borbone N, Oliviero G, Zamay TN, Moryachkov RV, Kolovskaya OS, Lukyanenko KA, Song Y, Merkuleva IA, Zabluda VN, Peters G, Koroleva LS, Veprintsev DV, Glazyrin YE, Volosnikova EA, Belenkaya SV, Esina TI, Isaeva AA, Nesmeyanova VS, Shanshin DV, Berlina AN, Komova NS, Svetlichnyi VA, Silnikov VN, Shcherbakov DN, Zamay GS, Zamay SS, Smolyarova T, Tikhonova EP, Chen KH, Jeng US, Condorelli G, de Franciscis V, Groenhof G, Yang C, Moskovsky AA, Fedorov DG, Tomilin FN, Tan W, Alexeev Y, Berezovski MV, Kichkailo AS. Mironov V, et al. Among authors: de franciscis v. Chemistry. 2022 Feb 24;28(12):e202104481. doi: 10.1002/chem.202104481. Epub 2022 Feb 9. Chemistry. 2022. PMID: 35025110 Free PMC article.
Selection of a Nuclease-Resistant RNA Aptamer Targeting CD19.
Esposito CL, Van Roosbroeck K, Santamaria G, Rotoli D, Sandomenico A, Wierda WG, Ferrajoli A, Ruvo M, Calin GA, de Franciscis V, Catuogno S. Esposito CL, et al. Among authors: de franciscis v. Cancers (Basel). 2021 Oct 18;13(20):5220. doi: 10.3390/cancers13205220. Cancers (Basel). 2021. PMID: 34680368 Free PMC article.
Aptamers: Cutting edge of cancer therapies.
Shigdar S, Schrand B, Giangrande PH, de Franciscis V. Shigdar S, et al. Among authors: de franciscis v. Mol Ther. 2021 Aug 4;29(8):2396-2411. doi: 10.1016/j.ymthe.2021.06.010. Epub 2021 Jun 17. Mol Ther. 2021. PMID: 34146729 Free PMC article. Review.
Identification of a novel RNA aptamer that selectively targets breast cancer exosomes.
Esposito CL, Quintavalle C, Ingenito F, Rotoli D, Roscigno G, Nuzzo S, Thomas R, Catuogno S, de Franciscis V, Condorelli G. Esposito CL, et al. Among authors: de franciscis v. Mol Ther Nucleic Acids. 2021 Jan 20;23:982-994. doi: 10.1016/j.omtn.2021.01.012. eCollection 2021 Mar 5. Mol Ther Nucleic Acids. 2021. PMID: 33614245 Free PMC article.
Axl-148b chimeric aptamers inhibit breast cancer and melanoma progression.
Quirico L, Orso F, Esposito CL, Bertone S, Coppo R, Conti L, Catuogno S, Cavallo F, de Franciscis V, Taverna D. Quirico L, et al. Among authors: de franciscis v. Int J Biol Sci. 2020 Feb 10;16(7):1238-1251. doi: 10.7150/ijbs.39768. eCollection 2020. Int J Biol Sci. 2020. PMID: 32174798 Free PMC article.
134 results