de Esch I - Search Results

1

Interrogating the Essential Bacterial Cell Division Protein FtsQ with Fragments Using Target Immobilized NMR Screening (TINS).

Glas M, Ab E, Hollander J, Siegal G, Luirink J, de Esch I. Glas M, et al. Among authors: de esch i. Int J Mol Sci. 2019 Jul 27;20(15):3684. doi: 10.3390/ijms20153684. Int J Mol Sci. 2019. PMID: 31357624 Free PMC article.

2

Crystal structure of the EphA4 protein tyrosine kinase domain in the apo- and dasatinib-bound state.

Farenc C, Celie PH, Tensen CP, de Esch IJ, Siegal G. Farenc C, et al. FEBS Lett. 2011 Nov 16;585(22):3593-9. doi: 10.1016/j.febslet.2011.10.028. Epub 2011 Oct 22. FEBS Lett. 2011. PMID: 22036717 Free article.

3

Fragment based lead discovery of small molecule inhibitors for the EPHA4 receptor tyrosine kinase.

van Linden OP, Farenc C, Zoutman WH, Hameetman L, Wijtmans M, Leurs R, Tensen CP, Siegal G, de Esch IJ. van Linden OP, et al. Eur J Med Chem. 2012 Jan;47(1):493-500. doi: 10.1016/j.ejmech.2011.11.020. Epub 2011 Nov 18. Eur J Med Chem. 2012. PMID: 22137457

4

Chemical subtleties in small-molecule modulation of peptide receptor function: the case of CXCR3 biaryl-type ligands.

Wijtmans M, Scholten DJ, Roumen L, Canals M, Custers H, Glas M, Vreeker MC, de Kanter FJ, de Graaf C, Smit MJ, de Esch IJ, Leurs R. Wijtmans M, et al. J Med Chem. 2012 Dec 13;55(23):10572-83. doi: 10.1021/jm301240t. Epub 2012 Nov 14. J Med Chem. 2012. PMID: 23150943

5

The Soluble Periplasmic Domains of Escherichia coli Cell Division Proteins FtsQ/FtsB/FtsL Form a Trimeric Complex with Submicromolar Affinity.

Glas M, van den Berg van Saparoea HB, McLaughlin SH, Roseboom W, Liu F, Koningstein GM, Fish A, den Blaauwen T, Heck AJ, de Jong L, Bitter W, de Esch IJ, Luirink J. Glas M, et al. J Biol Chem. 2015 Aug 28;290(35):21498-509. doi: 10.1074/jbc.M115.654756. Epub 2015 Jul 9. J Biol Chem. 2015. PMID: 26160297 Free PMC article.

6

EPHA4 is overexpressed but not functionally active in Sézary syndrome.

Hameetman L, van der Fits L, Zoutman WH, Out-Luiting JJ, Siegal G, de Esch IJ, Vermeer MH, Tensen CP. Hameetman L, et al. Oncotarget. 2015 Oct 13;6(31):31868-76. doi: 10.18632/oncotarget.5573. Oncotarget. 2015. PMID: 26376612 Free PMC article.

7

To Target or Not to Target Schistosoma mansoni Cyclic Nucleotide Phosphodiesterase 4A?

Zheng Y, Schroeder S, Kanev GK, Botros SS, William S, Sabra AA, Maes L, Caljon G, Gil C, Martinez A, Salado IG, Augustyns K, Edink E, Sijm M, de Heuvel E, de Esch IJP, van der Meer T, Siderius M, Sterk GJ, Brown D, Leurs R. Zheng Y, et al. Among authors: de esch ijp. Int J Mol Sci. 2023 Apr 6;24(7):6817. doi: 10.3390/ijms24076817. Int J Mol Sci. 2023. PMID: 37047792 Free PMC article.

8

Development of surface plasmon resonance biosensor assays for primary and secondary screening of acetylcholine binding protein ligands.

Retra K, Geitmann M, Kool J, Smit AB, de Esch IJ, Danielson UH, Irth H. Retra K, et al. Anal Biochem. 2010 Dec 1;407(1):58-64. doi: 10.1016/j.ab.2010.06.021. Epub 2010 Jun 17. Anal Biochem. 2010. PMID: 20599657

9

Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands.

de Kloe GE, Retra K, Geitmann M, Källblad P, Nahar T, van Elk R, Smit AB, van Muijlwijk-Koezen JE, Leurs R, Irth H, Danielson UH, de Esch IJ. de Kloe GE, et al. J Med Chem. 2010 Oct 14;53(19):7192-201. doi: 10.1021/jm100834y. J Med Chem. 2010. PMID: 20828128

10

CXCR3 antagonists: quaternary ammonium salts equipped with biphenyl- and polycycloaliphatic-anchors.

Wijtmans M, Verzijl D, Bergmans S, Lai M, Bosch L, Smit MJ, de Esch IJ, Leurs R. Wijtmans M, et al. Bioorg Med Chem. 2011 Jun 1;19(11):3384-93. doi: 10.1016/j.bmc.2011.04.035. Epub 2011 Apr 24. Bioorg Med Chem. 2011. PMID: 21570852

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

185 results

Search Page