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Neuronal P2X7 Receptor: Involvement in Neuronal Physiology and Pathology.
Miras-Portugal MT, Sebastián-Serrano Á, de Diego García L, Díaz-Hernández M. Miras-Portugal MT, et al. Among authors: de diego garcia l. J Neurosci. 2017 Jul 26;37(30):7063-7072. doi: 10.1523/JNEUROSCI.3104-16.2017. J Neurosci. 2017. PMID: 28747389 Free PMC article. Review.
Tissue-nonspecific Alkaline Phosphatase Regulates Purinergic Transmission in the Central Nervous System During Development and Disease.
Sebastián-Serrano Á, de Diego-García L, Martínez-Frailes C, Ávila J, Zimmermann H, Millán JL, Miras-Portugal MT, Díaz-Hernández M. Sebastián-Serrano Á, et al. Among authors: de diego garcia l. Comput Struct Biotechnol J. 2014 Dec 15;13:95-100. doi: 10.1016/j.csbj.2014.12.004. eCollection 2015. Comput Struct Biotechnol J. 2014. PMID: 25709758 Free PMC article. Review.
Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation.
Sebastián-Serrano Á, Engel T, de Diego-García L, Olivos-Oré LA, Arribas-Blázquez M, Martínez-Frailes C, Pérez-Díaz C, Millán JL, Artalejo AR, Miras-Portugal MT, Henshall DC, Díaz-Hernández M. Sebastián-Serrano Á, et al. Among authors: de diego garcia l. Hum Mol Genet. 2016 Oct 1;25(19):4143-4156. doi: 10.1093/hmg/ddw248. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466191 Free PMC article.
The regulation of proteostasis in glial cells by nucleotide receptors is key in acute neuroinflammation.
de Diego García L, Sebastián-Serrano Á, Hernández IH, Pintor J, Lucas JJ, Díaz-Hernández M. de Diego García L, et al. FASEB J. 2018 Jun;32(6):3020-3032. doi: 10.1096/fj.201701064RR. Epub 2018 Jan 11. FASEB J. 2018. PMID: 29401585
Finally, our findings point to the design of selective P2Y(2)R agonist drugs as a new therapeutic approach to treat the neuroinflammatory status.-De Diego Garcia, L., Sebastian-Serrano, A., Hernandez, I. H., Pintor, J., Lucas, J. ...
Finally, our findings point to the design of selective P2Y(2)R agonist drugs as a new therapeutic approach to treat the neuroinflammatory st …
The Neurotoxic Role of Extracellular Tau Protein.
Sebastián-Serrano Á, de Diego-García L, Díaz-Hernández M. Sebastián-Serrano Á, et al. Among authors: de diego garcia l. Int J Mol Sci. 2018 Mar 27;19(4):998. doi: 10.3390/ijms19040998. Int J Mol Sci. 2018. PMID: 29584657 Free PMC article. Review.
Amyloid Peptide Induced Neuroinflammation Increases the P2X7 Receptor Expression in Microglial Cells, Impacting on Its Functionality.
Martínez-Frailes C, Di Lauro C, Bianchi C, de Diego-García L, Sebastián-Serrano Á, Boscá L, Díaz-Hernández M. Martínez-Frailes C, et al. Among authors: de diego garcia l. Front Cell Neurosci. 2019 Apr 12;13:143. doi: 10.3389/fncel.2019.00143. eCollection 2019. Front Cell Neurosci. 2019. PMID: 31031598 Free PMC article.
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