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Tert-butyl 4-((1-phenyl-1H-pyrazol-4-yl) methyl) piperazine-1-carboxylate (LQFM104)- New piperazine derivative with antianxiety and antidepressant-like effects: Putative role of serotonergic system.
da Silva DM, Sanz G, Vaz BG, de Carvalho FS, Lião LM, de Oliveira DR, Moreira LKDS, Cardoso CS, de Brito AF, da Silva DPB, da Rocha FF, Santana IGC, Galdino PM, Costa EA, Menegatti R. da Silva DM, et al. Among authors: de brito af, de carvalho fs, de oliveira dr. Biomed Pharmacother. 2018 Jul;103:546-552. doi: 10.1016/j.biopha.2018.04.077. Epub 2018 Apr 24. Biomed Pharmacother. 2018. PMID: 29677541
Cytotoxicity and antiangiogenic activity of grandisin.
Valadares MC, de Carvalho IC, de Oliveira Junior L, Vieira Mde S, Benfica PL, de Carvalho FS, Andrade LV, Lima EM, Kato MJ. Valadares MC, et al. Among authors: de carvalho ic, de oliveira junior l, de carvalho fs. J Pharm Pharmacol. 2009 Dec;61(12):1709-14. doi: 10.1211/jpp/61.12.0017. J Pharm Pharmacol. 2009. PMID: 19958595
Structure-activity relationship of three new piperazine derivates with anxiolytic-like and antidepressant-like effects.
Santana IGC, Almeida LS, Moreira LKDS, de Carvalho FS, Menegatti R, da Rocha ALB, Mazurok TA, Vaz BG, Lião LM, Brito AF, Fajemiroye JO, Costa EA, de Carvalho PMG. Santana IGC, et al. Among authors: de carvalho fs. Can J Physiol Pharmacol. 2022 Jun 1;100(6):521-533. doi: 10.1139/cjpp-2021-0729. Epub 2022 Apr 8. Can J Physiol Pharmacol. 2022. PMID: 35395172
LQFM030 reduced Ehrlich ascites tumor cell proliferation and VEGF levels.
da Mota MF, de Carvalho FS, de Ávila RI, de Ávila PHM, Cortez AP, Menegatti R, Sabino JR, Dos Santos TRM, Gomes SA, da Cunha LC, Valadares MC. da Mota MF, et al. Among authors: de avila ri, de avila phm, de carvalho fs. Life Sci. 2018 May 15;201:1-8. doi: 10.1016/j.lfs.2017.12.029. Epub 2017 Dec 24. Life Sci. 2018. PMID: 29278686
Antiangiogenic and antitumoral activity of LQFM126 prototype against B16F10 melanoma cells.
Garcia da Silva AC, Rodrigues BDS, Andrade WM, Marques Dos Santos TR, de Carvalho FS, Sanz G, Vaz BG, Lião LM, Menegatti R, Valadares MC. Garcia da Silva AC, et al. Among authors: de carvalho fs. Chem Biol Interact. 2020 Jul 1;325:109127. doi: 10.1016/j.cbi.2020.109127. Epub 2020 May 11. Chem Biol Interact. 2020. PMID: 32437695
Preclinical pharmacokinetics of a promising antineoplastic prototype piperazine-containing compound (LQFM018) in rats by a new LC-MS/MS bioanalytical method.
Rodrigues AR, Rodrigues CR, Gomes SA, Marques SM, Naves LM, Pedrino GR, de Oliveira-Neto JR, de Carvalho FS, Cruz A, Lião LM, Menegatti R, Carlos da Cunha L. Rodrigues AR, et al. Among authors: de carvalho fs. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 May 15;1223:123710. doi: 10.1016/j.jchromb.2023.123710. Epub 2023 Apr 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 37068313
Anti-inflammatory, antinociceptive, and vasorelaxant effects of a new pyrazole compound 5-(1-(2-fluorophenyl)-1H-pyrazol-4-yl)-1H-tetrazole: role of NO/cGMP pathway and calcium channels.
de Oliveira LP, Florentino IF, Silva DPB, Pazini F, de Carvalho FS, Sanz G, Vaz BG, da Rocha FF, Fajemiroye JO, Ghedini PC, Lião LM, Menegatti R, Costa EA, de Oliveira TS. de Oliveira LP, et al. Among authors: de carvalho fs. Can J Physiol Pharmacol. 2023 May 1;101(5):216-225. doi: 10.1139/cjpp-2022-0428. Epub 2023 Mar 3. Can J Physiol Pharmacol. 2023. PMID: 36866837
31 results