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How is Big Data reshaping preclinical aging research?
Fernandez ME, Martinez-Romero J, Aon MA, Bernier M, Price NL, de Cabo R. Fernandez ME, et al. Among authors: de cabo r. Lab Anim (NY). 2023 Dec;52(12):289-314. doi: 10.1038/s41684-023-01286-y. Epub 2023 Nov 28. Lab Anim (NY). 2023. PMID: 38017182 Review.
Gene body DNA hydroxymethylation restricts the magnitude of transcriptional changes during aging.
Occean JR, Yang N, Sun Y, Dawkins MS, Munk R, Belair C, Dar S, Anerillas C, Wang L, Shi C, Dunn C, Bernier M, Price NL, Kim JS, Cui CY, Fan J, Bhattacharyya M, De S, Maragkakis M, deCabo R, Sidoli S, Sen P. Occean JR, et al. bioRxiv [Preprint]. 2023 Feb 15:2023.02.15.528714. doi: 10.1101/2023.02.15.528714. bioRxiv. 2023. PMID: 36824863 Free PMC article. Preprint.
Prolonged fasting times reap greater geroprotective effects when combined with caloric restriction in adult female mice.
Duregon E, Fernandez ME, Martinez Romero J, Di Germanio C, Cabassa M, Voloshchuk R, Ehrlich-Mora MR, Moats JM, Wong S, Bosompra O, Rudderow A, Morrell CH, Camandola S, Price NL, Aon MA, Bernier M, de Cabo R. Duregon E, et al. Among authors: de cabo r. Cell Metab. 2023 Jul 11;35(7):1179-1194.e5. doi: 10.1016/j.cmet.2023.05.003. Cell Metab. 2023. PMID: 37437544
Survey of organ-derived small extracellular vesicles and particles (sEVPs) to identify selective protein markers in mouse serum.
Abdelmohsen K, Herman AB, Carr AE, Henry-Smith CA, Rossi M, Meng Q, Yang JH, Tsitsipatis D, Bangura A, Munk R, Martindale JL, Nogueras-Ortiz CJ, Hao J, Gong Y, Liu Y, Cui CY, Hartnell LM, Price NL, Ferrucci L, Kapogiannis D, de Cabo R, Gorospe M. Abdelmohsen K, et al. Among authors: de cabo r. J Extracell Biol. 2023 Aug;2(8):e106. doi: 10.1002/jex2.106. Epub 2023 Aug 22. J Extracell Biol. 2023. PMID: 37744304 Free PMC article.
Preclinical and translational models for delirium: Recommendations for future research from the NIDUS delirium network.
Vasunilashorn SM, Lunardi N, Newman JC, Crosby G, Acker L, Abel T, Bhatnagar S, Cunningham C, de Cabo R, Dugan L, Hippensteel JA, Ishizawa Y, Lahiri S, Marcantonio ER, Xie Z, Inouye SK, Terrando N, Eckenhoff RG; NIDUS Delirium Network. Vasunilashorn SM, et al. Among authors: de cabo r. Alzheimers Dement. 2023 May;19(5):2150-2174. doi: 10.1002/alz.12941. Epub 2023 Feb 17. Alzheimers Dement. 2023. PMID: 36799408 Free PMC article. Review.
Biology of Stress Responses in Aging.
Maragkakis M, Malla S, Hatzoglou M, Trifunovic A, Glick AB, Finkel T, Longo VD, Kaushik S, Muñoz-Cánoves P, Lithgow GJ, Naidoo N, Booth LN, Payea MJ, Herman AB, de Cabo R, Wilson DM, Ferrucci L, Gorospe M. Maragkakis M, et al. Among authors: de cabo r. Aging Biol. 2023;1:20230002. doi: 10.59368/agingbio.20230001. Epub 2023 Jun 27. Aging Biol. 2023. PMID: 38500537 Free PMC article.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: de cabo r, de s. bioRxiv [Preprint]. 2023 Feb 15:2023.02.14.528512. doi: 10.1101/2023.02.14.528512. bioRxiv. 2023. PMID: 36824822 Free PMC article. Updated. Preprint.
A hyper-quiescent chromatin state formed during aging is reversed by regeneration.
Yang N, Occean JR, Melters DP, Shi C, Wang L, Stransky S, Doyle ME, Cui CY, Delannoy M, Fan J, Slama E, Egan JM, De S, Cunningham SC, de Cabo R, Sidoli S, Dalal Y, Sen P. Yang N, et al. Among authors: de cabo r, de s. Mol Cell. 2023 May 18;83(10):1659-1676.e11. doi: 10.1016/j.molcel.2023.04.005. Epub 2023 Apr 27. Mol Cell. 2023. PMID: 37116496 Free article.
A small erythropoietin derived non-hematopoietic peptide reduces cardiac inflammation, attenuates age associated declines in heart function and prolongs healthspan.
Winicki NM, Nanavati AP, Morrell CH, Moen JM, Axsom JE, Krawczyk M, Petrashevskaya NN, Beyman MG, Ramirez C, Alfaras I, Mitchell SJ, Juhaszova M, Riordon DR, Wang M, Zhang J, Cerami A, Brines M, Sollott SJ, de Cabo R, Lakatta EG. Winicki NM, et al. Among authors: de cabo r. Front Cardiovasc Med. 2023 Jan 18;9:1096887. doi: 10.3389/fcvm.2022.1096887. eCollection 2022. Front Cardiovasc Med. 2023. PMID: 36741836 Free PMC article.
367 results