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PLK1 inhibition dampens NLRP3 inflammasome-elicited response in inflammatory disease models.
Baldrighi M, Doreth C, Li Y, Zhao X, Warner E, Chenoweth H, Kishore K, Umrania Y, Minde DP, Thome S, Yu X, Lu Y, Knapton A, Harrison J, Clarke M, Latz E, de Cárcer G, Malumbres M, Ryffel B, Bryant C, Liu J, Lilley KS, Mallat Z, Li X. Baldrighi M, et al. Among authors: de carcer g. J Clin Invest. 2023 Nov 1;133(21):e162129. doi: 10.1172/JCI162129. J Clin Invest. 2023. PMID: 37698938 Free PMC article.
Targeting cell cycle kinases for cancer therapy.
de Cárcer G, Pérez de Castro I, Malumbres M. de Cárcer G, et al. Curr Med Chem. 2007;14(9):969-85. doi: 10.2174/092986707780362925. Curr Med Chem. 2007. PMID: 17439397 Review.
Emerging cancer therapeutic opportunities by inhibiting mitotic kinases.
Pérez de Castro I, de Cárcer G, Montoya G, Malumbres M. Pérez de Castro I, et al. Among authors: de carcer g. Curr Opin Pharmacol. 2008 Aug;8(4):375-83. doi: 10.1016/j.coph.2008.06.013. Epub 2008 Jul 30. Curr Opin Pharmacol. 2008. PMID: 18644252 Review.
TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis.
Muñoz P, Blanco R, de Carcer G, Schoeftner S, Benetti R, Flores JM, Malumbres M, Blasco MA. Muñoz P, et al. Among authors: de carcer g. Mol Cell Biol. 2009 Mar;29(6):1608-25. doi: 10.1128/MCB.01339-08. Epub 2009 Jan 5. Mol Cell Biol. 2009. PMID: 19124610 Free PMC article.
RINGO C is required to sustain the spindle-assembly checkpoint.
Mourón S, de Cárcer G, Seco E, Fernández-Miranda G, Malumbres M, Nebreda AR. Mourón S, et al. Among authors: de carcer g. J Cell Sci. 2010 Aug 1;123(Pt 15):2586-95. doi: 10.1242/jcs.059964. Epub 2010 Jul 6. J Cell Sci. 2010. PMID: 20605920
39 results