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Pharmacokinetic analysis of vilobelimab, anaphylatoxin C5a and antidrug antibodies in PANAMO: a phase 3 study in critically ill,  invasively mechanically ventilated COVID-19 patients.
Lim EHT, Vlaar APJ, de Bruin S, Rückinger S, Thielert C, Habel M, Guo R, Burnett BP, Dickinson J, Brouwer MC, Riedemann NC, van de Beek D; PANAMO study group. Lim EHT, et al. Among authors: de bruin s. Intensive Care Med Exp. 2023 Jun 19;11(1):37. doi: 10.1186/s40635-023-00520-8. Intensive Care Med Exp. 2023. PMID: 37332066 Free PMC article.
Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine.
Vlaar AP, Oczkowski S, de Bruin S, Wijnberge M, Antonelli M, Aubron C, Aries P, Duranteau J, Juffermans NP, Meier J, Murphy GJ, Abbasciano R, Muller M, Shah A, Perner A, Rygaard S, Walsh TS, Guyatt G, Dionne JC, Cecconi M. Vlaar AP, et al. Among authors: de bruin s. Intensive Care Med. 2020 Apr;46(4):673-696. doi: 10.1007/s00134-019-05884-8. Epub 2020 Jan 7. Intensive Care Med. 2020. PMID: 31912207 Free PMC article.
Guidelines seek unbiased recommendations.
Vlaar AP, Oczkowski S, Murphy GJ, Perner A, Guyatt G, Dionne JC, Cecconi M; ESICM Transfusion Task Force. Vlaar AP, et al. Intensive Care Med. 2020 May;46(5):1065-1069. doi: 10.1007/s00134-020-05968-w. Epub 2020 Mar 2. Intensive Care Med. 2020. PMID: 32123992 No abstract available.
Anti-C5a antibody IFX-1 (vilobelimab) treatment versus best supportive care for patients with severe COVID-19 (PANAMO): an exploratory, open-label, phase 2 randomised controlled trial.
Vlaar APJ, de Bruin S, Busch M, Timmermans SAMEG, van Zeggeren IE, Koning R, Ter Horst L, Bulle EB, van Baarle FEHP, van de Poll MCG, Kemper EM, van der Horst ICC, Schultz MJ, Horn J, Paulus F, Bos LD, Wiersinga WJ, Witzenrath M, Rueckinger S, Pilz K, Brouwer MC, Guo RF, Heunks L, van Paassen P, Riedemann NC, van de Beek D. Vlaar APJ, et al. Among authors: de bruin s. Lancet Rheumatol. 2020 Dec;2(12):e764-e773. doi: 10.1016/S2665-9913(20)30341-6. Epub 2020 Sep 28. Lancet Rheumatol. 2020. PMID: 33015643 Free PMC article.
Treating critically ill anemic patients with erythropoietin: less is more.
Oczkowski S, Shah A, Aubron C, Wijnberge M, Vlaar APJ; ESICM Transfusion Guideline Part 1 Task force. Oczkowski S, et al. Intensive Care Med. 2021 Feb;47(2):256-257. doi: 10.1007/s00134-020-06259-0. Epub 2020 Oct 9. Intensive Care Med. 2021. PMID: 33034687 No abstract available.
Distinct cellular immune profiles in the airways and blood of critically ill patients with COVID-19.
Saris A, Reijnders TDY, Nossent EJ, Schuurman AR, Verhoeff J, Asten SV, Bontkes H, Blok S, Duitman J, Bogaard HJ, Heunks L, Lutter R, van der Poll T, Garcia Vallejo JJ; ArtDECO consortium and the Amsterdam UMC COVID study group. Saris A, et al. Thorax. 2021 Oct;76(10):1010-1019. doi: 10.1136/thoraxjnl-2020-216256. Epub 2021 Apr 12. Thorax. 2021. PMID: 33846275 Free PMC article.
178 results