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Evaluation of drug penetration into the brain: a double study by in vivo imaging with positron emission tomography and using an in vitro model of the human blood-brain barrier.
Josserand V, Pélerin H, de Bruin B, Jego B, Kuhnast B, Hinnen F, Ducongé F, Boisgard R, Beuvon F, Chassoux F, Daumas-Duport C, Ezan E, Dollé F, Mabondzo A, Tavitian B. Josserand V, et al. Among authors: de bruin b. J Pharmacol Exp Ther. 2006 Jan;316(1):79-86. doi: 10.1124/jpet.105.089102. Epub 2005 Oct 6. J Pharmacol Exp Ther. 2006. PMID: 16210395
Two new convenient syntheses of 14C-squalene from turbinaric acid.
Philippe N, Rivron L, De Bruin B, Schofield J, Roy S. Philippe N, et al. Among authors: de bruin b. J Labelled Comp Radiopharm. 2018 Oct;61(12):878-884. doi: 10.1002/jlcr.3672. Epub 2018 Sep 10. J Labelled Comp Radiopharm. 2018. PMID: 30066967
Effect of deuteration on the metabolism and clearance of some pharmacologically active compounds--synthesis and in vitro metabolism of deuterated derivatives of dronedadrone.
Schofield J, Brasseur D, de Bruin B, Vassal T, Klieber S, Arabeyre C, Bourrié M, Sadoun F, Fabre G. Schofield J, et al. Among authors: de bruin b. J Labelled Comp Radiopharm. 2013 Jul-Aug;56(9-10):504-12. doi: 10.1002/jlcr.3090. Epub 2013 Sep 4. J Labelled Comp Radiopharm. 2013. PMID: 24285529
N-Heterocyclic Carbene Analogues of Wittig Hydrocarbon.
Steffenfauseweh H, Vishnevskiy YV, Neumann B, Stammler HG, de Bruin B, Ghadwal RS. Steffenfauseweh H, et al. Among authors: de bruin b. Chemistry. 2024 May 8;30(26):e202400879. doi: 10.1002/chem.202400879. Epub 2024 Apr 16. Chemistry. 2024. PMID: 38437163
233 results