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Improvement of antimalarial activity of a 3-alkylpiridine alkaloid analog by replacing the pyridine ring to a thiazole-containing heterocycle: Mode of action, mutagenicity profile, and Caco-2 cell-based permeability.
Guimarães DSM, de Sousa Luz LS, do Nascimento SB, Silva LR, de Miranda Martins NR, de Almeida HG, de Souza Reis V, Maluf SEC, Budu A, Marinho JA, Abramo C, Carmona AK, da Silva MG, da Silva GR, Kemmer VM, Butera AP, Ribeiro-Viana RM, Gazarini ML, Júnior CSN, Guimarães L, Dos Santos FV, de Castro WV, Viana GHR, de Brito CFA, de Pilla Varotti F. Guimarães DSM, et al. Among authors: de brito cfa. Eur J Pharm Sci. 2019 Oct 1;138:105015. doi: 10.1016/j.ejps.2019.105015. Epub 2019 Jul 22. Eur J Pharm Sci. 2019. PMID: 31344442
A Comprehensive Analysis of the Genetic Diversity of Plasmodium falciparum Histidine-Rich Protein 2 (PfHRP2) in the Brazilian Amazon.
Costa GL, Mascarenhas MEP, Martin TOG, Fortini LG, Louzada J, Pereira DB, Aguiar ACC, Carvalho LH, de Brito CFA, Fontes CJF, de Sousa TN. Costa GL, et al. Among authors: de brito cfa. Front Cell Infect Microbiol. 2021 Sep 21;11:742681. doi: 10.3389/fcimb.2021.742681. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34621693 Free PMC article.
Outbreak of human malaria caused by Plasmodium simium in the Atlantic Forest in Rio de Janeiro: a molecular epidemiological investigation.
Brasil P, Zalis MG, de Pina-Costa A, Siqueira AM, Júnior CB, Silva S, Areas ALL, Pelajo-Machado M, de Alvarenga DAM, da Silva Santelli ACF, Albuquerque HG, Cravo P, Santos de Abreu FV, Peterka CL, Zanini GM, Suárez Mutis MC, Pissinatti A, Lourenço-de-Oliveira R, de Brito CFA, de Fátima Ferreira-da-Cruz M, Culleton R, Daniel-Ribeiro CT. Brasil P, et al. Among authors: de alvarenga dam, de brito cfa, de fatima ferreira da cruz m, de pina costa a. Lancet Glob Health. 2017 Oct;5(10):e1038-e1046. doi: 10.1016/S2214-109X(17)30333-9. Epub 2017 Aug 31. Lancet Glob Health. 2017. PMID: 28867401 Free article.
Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combination therapy with primaquine.
Daher A, Aljayyoussi G, Pereira D, Lacerda MVG, Alexandre MAA, Nascimento CT, Alves JC, da Fonseca LB, da Silva DMD, Pinto DP, Rodrigues DF, Silvino ACR, de Sousa TN, de Brito CFA, Ter Kuile FO, Lalloo DG. Daher A, et al. Among authors: de brito cfa. Malar J. 2019 Sep 23;18(1):325. doi: 10.1186/s12936-019-2950-4. Malar J. 2019. PMID: 31547827 Free PMC article. Clinical Trial.
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