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A New Old Target: Androgen Receptor Signaling and Advanced Prostate Cancer.
Westaby D, Fenor de La Maza MLD, Paschalis A, Jimenez-Vacas JM, Welti J, de Bono J, Sharp A. Westaby D, et al. Among authors: de bono j. Annu Rev Pharmacol Toxicol. 2022 Jan 6;62:131-153. doi: 10.1146/annurev-pharmtox-052220-015912. Epub 2021 Aug 24. Annu Rev Pharmacol Toxicol. 2022. PMID: 34449248 Review.
First-in-human Phase I study of EZN-4176, a locked nucleic acid antisense oligonucleotide to exon 4 of the androgen receptor mRNA in patients with castration-resistant prostate cancer.
Bianchini D, Omlin A, Pezaro C, Lorente D, Ferraldeschi R, Mukherji D, Crespo M, Figueiredo I, Miranda S, Riisnaes R, Zivi A, Buchbinder A, Rathkopf DE, Attard G, Scher HI, de Bono J, Danila DC. Bianchini D, et al. Among authors: de bono j. Br J Cancer. 2013 Nov 12;109(10):2579-86. doi: 10.1038/bjc.2013.619. Epub 2013 Oct 29. Br J Cancer. 2013. PMID: 24169353 Free PMC article. Clinical Trial.
Management of patients with castration-resistant disease.
Pezaro C, Omlin A, Lorente D, de Bono J. Pezaro C, et al. Among authors: de bono j. Hematol Oncol Clin North Am. 2013 Dec;27(6):1243-60, ix. doi: 10.1016/j.hoc.2013.08.008. Epub 2013 Sep 20. Hematol Oncol Clin North Am. 2013. PMID: 24188261 Review.
823 results