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Inhibition of DHCR24 activates LXRα to ameliorate hepatic steatosis and inflammation.
Zhou E, Ge X, Nakashima H, Li R, van der Zande HJP, Liu C, Li Z, Müller C, Bracher F, Mohammed Y, de Boer JF, Kuipers F, Guigas B, Glass CK, Rensen PCN, Giera M, Wang Y. Zhou E, et al. Among authors: de boer jf. EMBO Mol Med. 2023 Aug 7;15(8):e16845. doi: 10.15252/emmm.202216845. Epub 2023 Jun 26. EMBO Mol Med. 2023. PMID: 37357756 Free PMC article.
Glucose-6-Phosphate Regulates Hepatic Bile Acid Synthesis in Mice.
Hoogerland JA, Lei Y, Wolters JC, de Boer JF, Bos T, Bleeker A, Mulder NL, van Dijk TH, Kuivenhoven JA, Rajas F, Mithieux G, Haeusler RA, Verkade HJ, Bloks VW, Kuipers F, Oosterveer MH. Hoogerland JA, et al. Among authors: de boer jf. Hepatology. 2019 Dec;70(6):2171-2184. doi: 10.1002/hep.30778. Epub 2019 Jun 24. Hepatology. 2019. PMID: 31102537 Free PMC article.
Cholangiopathy and Biliary Fibrosis in Cyp2c70-Deficient Mice Are Fully Reversed by Ursodeoxycholic Acid.
de Boer JF, de Vries HD, Palmiotti A, Li R, Doestzada M, Hoogerland JA, Fu J, La Rose AM, Westerterp M, Mulder NL, Hovingh MV, Koehorst M, Kloosterhuis NJ, Wolters JC, Bloks VW, Haas JT, Dombrowicz D, Staels B, van de Sluis B, Kuipers F. de Boer JF, et al. Among authors: de vries hd. Cell Mol Gastroenterol Hepatol. 2021;11(4):1045-1069. doi: 10.1016/j.jcmgh.2020.12.004. Epub 2020 Dec 10. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33309945 Free PMC article.
240 results