de Boer J - Search Results

1

ARHGEF4 Regulates an Essential Oncogenic Program in t(12;21)-Associated Acute Lymphoblastic Leukemia.

Virely C, Gasparoli L, Mangolini M, Clesham K, Inglott S, Edwards D, Adams S, Bartram J, Samarasinghe S, Ancliff P, Vora A, de Boer J, Williams O. Virely C, et al. Among authors: de boer j. Hemasphere. 2020 Sep 11;4(5):e467. doi: 10.1097/HS9.0000000000000467. eCollection 2020 Oct. Hemasphere. 2020. PMID: 32984770 Free PMC article.

2

Acute myeloid leukemia induced by MLL-ENL is cured by oncogene ablation despite acquisition of complex genetic abnormalities.

Horton SJ, Walf-Vorderwülbecke V, Chatters SJ, Sebire NJ, de Boer J, Williams O. Horton SJ, et al. Among authors: de boer j. Blood. 2009 May 14;113(20):4922-9. doi: 10.1182/blood-2008-07-170480. Epub 2008 Nov 24. Blood. 2009. PMID: 19029444 Free article.

3

ERG is a megakaryocytic oncogene.

Salek-Ardakani S, Smooha G, de Boer J, Sebire NJ, Morrow M, Rainis L, Lee S, Williams O, Izraeli S, Brady HJ. Salek-Ardakani S, et al. Among authors: de boer j. Cancer Res. 2009 Jun 1;69(11):4665-73. doi: 10.1158/0008-5472.CAN-09-0075. Cancer Res. 2009. PMID: 19487285

4

Tnfaip8 is an essential gene for the regulation of glucocorticoid-mediated apoptosis of thymocytes.

Woodward MJ, de Boer J, Heidorn S, Hubank M, Kioussis D, Williams O, Brady HJ. Woodward MJ, et al. Among authors: de boer j. Cell Death Differ. 2010 Feb;17(2):316-23. doi: 10.1038/cdd.2009.125. Epub 2009 Sep 4. Cell Death Differ. 2010. PMID: 19730441

5

The basic leucine zipper transcription factor E4BP4 is essential for natural killer cell development.

Gascoyne DM, Long E, Veiga-Fernandes H, de Boer J, Williams O, Seddon B, Coles M, Kioussis D, Brady HJ. Gascoyne DM, et al. Among authors: de boer j. Nat Immunol. 2009 Oct;10(10):1118-24. doi: 10.1038/ni.1787. Epub 2009 Sep 13. Nat Immunol. 2009. PMID: 19749763

6

The E2A-HLF oncogenic fusion protein acts through Lmo2 and Bcl-2 to immortalize hematopoietic progenitors.

de Boer J, Yeung J, Ellu J, Ramanujachar R, Bornhauser B, Solarska O, Hubank M, Williams O, Brady HJ. de Boer J, et al. Leukemia. 2011 Feb;25(2):321-30. doi: 10.1038/leu.2010.253. Epub 2010 Nov 12. Leukemia. 2011. PMID: 21072044

7

Dysregulation of the HIF pathway due to VHL mutation causing severe erythrocytosis and pulmonary arterial hypertension.

Bond J, Gale DP, Connor T, Adams S, de Boer J, Gascoyne DM, Williams O, Maxwell PH, Ancliff PJ. Bond J, et al. Among authors: de boer j. Blood. 2011 Mar 31;117(13):3699-701. doi: 10.1182/blood-2010-12-327569. Blood. 2011. PMID: 21454469 Free article. No abstract available.

8

Frat2 mediates the oncogenic activation of Rac by MLL fusions.

Walf-Vorderwülbecke V, de Boer J, Horton SJ, van Amerongen R, Proost N, Berns A, Williams O. Walf-Vorderwülbecke V, et al. Among authors: de boer j. Blood. 2012 Dec 6;120(24):4819-28. doi: 10.1182/blood-2012-05-432534. Epub 2012 Oct 16. Blood. 2012. PMID: 23074275 Free article.

9

The AAA+ ATPase RUVBL2 is a critical mediator of MLL-AF9 oncogenesis.

Osaki H, Walf-Vorderwülbecke V, Mangolini M, Zhao L, Horton SJ, Morrone G, Schuringa JJ, de Boer J, Williams O. Osaki H, et al. Among authors: de boer j. Leukemia. 2013 Jul;27(7):1461-8. doi: 10.1038/leu.2013.42. Epub 2013 Feb 13. Leukemia. 2013. PMID: 23403462

10

In focus: MLL-rearranged leukemia.

de Boer J, Walf-Vorderwülbecke V, Williams O. de Boer J, et al. Leukemia. 2013 Jun;27(6):1224-8. doi: 10.1038/leu.2013.78. Epub 2013 Mar 21. Leukemia. 2013. PMID: 23515098 Review.

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