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Resting natural killer cell homeostasis relies on tryptophan/NAD+ metabolism and HIF-1α.
Pelletier A, Nelius E, Fan Z, Khatchatourova E, Alvarado-Diaz A, He J, Krzywinska E, Sobecki M, Nagarajan S, Kerdiles Y, Fandrey J, Gotthardt D, Sexl V, de Bock K, Stockmann C. Pelletier A, et al. Among authors: de bock k. EMBO Rep. 2023 Jun 5;24(6):e56156. doi: 10.15252/embr.202256156. Epub 2023 Mar 29. EMBO Rep. 2023. PMID: 36987917 Free PMC article.
GDF15 increases insulin action in the liver and adipose tissue via a β-adrenergic receptor-mediated mechanism.
Sjøberg KA, Sigvardsen CM, Alvarado-Diaz A, Andersen NR, Larance M, Seeley RJ, Schjerling P, Knudsen JG, Katzilieris-Petras G, Clemmensen C, Jørgensen SB, De Bock K, Richter EA. Sjøberg KA, et al. Among authors: de bock k. Cell Metab. 2023 Aug 8;35(8):1327-1340.e5. doi: 10.1016/j.cmet.2023.06.016. Epub 2023 Jul 19. Cell Metab. 2023. PMID: 37473755
The vascular gene Apold1 is dispensable for normal development but controls angiogenesis under pathological conditions.
Fan Z, Ardicoglu R, Batavia AA, Rust R, von Ziegler L, Waag R, Zhang J, Desgeorges T, Sturman O, Dang H, Weber R, Roszkowski M, Moor AE, Schwab ME, Germain PL, Bohacek J, De Bock K. Fan Z, et al. Among authors: de bock k. Angiogenesis. 2023 Aug;26(3):385-407. doi: 10.1007/s10456-023-09870-z. Epub 2023 Mar 18. Angiogenesis. 2023. PMID: 36933174 Free PMC article.
Nucleolin promotes angiogenesis and endothelial metabolism along the oncofetal axis in the human brain vasculature.
Schwab M, de Trizio I, Ghobrial M, Shiu JY, Sürücü O, Girolamo F, Errede M, Yilmaz M, Haybaeck J, Moiraghi A, Monnier PP, Lawler SE, Greenfield JP, Radovanovic I, Frei K, Schlapbach R, Vogel V, Virgintino D, De Bock K, Wälchli T. Schwab M, et al. Among authors: de bock k. JCI Insight. 2023 Apr 24;8(8):e143071. doi: 10.1172/jci.insight.143071. JCI Insight. 2023. PMID: 36917178 Free PMC article.
Generation of allogenic and xenogeneic functional muscle stem cells for intramuscular transplantation.
Lenardič A, Domenig SA, Zvick J, Bundschuh N, Tarnowska-Sengül M, Furrer R, Noé FJ, Trautmann CLL, Ghosh A, Bacchin G, Gjonlleshaj P, Qabrati X, Masschelein E, De Bock K, Handschin C, Bar-Nur O. Lenardič A, et al. Among authors: de bock k. J Clin Invest. 2024 May 7:e166998. doi: 10.1172/JCI166998. Online ahead of print. J Clin Invest. 2024. PMID: 38713532
HIF1α-dependent uncoupling of glycolysis suppresses tumor cell proliferation.
Urrutia AA, Mesa-Ciller C, Guajardo-Grence A, Alkan HF, Soro-Arnáiz I, Vandekeere A, Ferreira Campos AM, Igelmann S, Fernández-Arroyo L, Rinaldi G, Lorendeau D, De Bock K, Fendt SM, Aragonés J. Urrutia AA, et al. Among authors: de bock k. Cell Rep. 2024 Apr 23;43(4):114103. doi: 10.1016/j.celrep.2024.114103. Epub 2024 Apr 11. Cell Rep. 2024. PMID: 38607920 Free PMC article.
Transcellular Barriers to Glucose Delivery in the Body.
Klip A, De Bock K, Bilan PJ, Richter EA. Klip A, et al. Among authors: de bock k. Annu Rev Physiol. 2024 Feb 12;86:149-173. doi: 10.1146/annurev-physiol-042022-031657. Annu Rev Physiol. 2024. PMID: 38345907 Free article. Review.
Combinatorial Treatment with PARP and MAPK Inhibitors Overcomes Phenotype Switch-Driven Drug Resistance in Advanced Melanoma.
Ferretti LP, Böhi F, Leslie Pedrioli DM, Cheng PF, Ferrari E, Baumgaertner P, Alvarado-Diaz A, Sella F, Cereghetti A, Turko P, Wright RH, De Bock K, Speiser DE, Ferrari R, Levesque MP, Hottiger MO. Ferretti LP, et al. Among authors: de bock k. Cancer Res. 2023 Dec 1;83(23):3974-3988. doi: 10.1158/0008-5472.CAN-23-0485. Cancer Res. 2023. PMID: 37729428
Shaping the brain vasculature in development and disease in the single-cell era.
Wälchli T, Bisschop J, Carmeliet P, Zadeh G, Monnier PP, De Bock K, Radovanovic I. Wälchli T, et al. Among authors: de bock k. Nat Rev Neurosci. 2023 May;24(5):271-298. doi: 10.1038/s41583-023-00684-y. Epub 2023 Mar 20. Nat Rev Neurosci. 2023. PMID: 36941369 Free PMC article. Review.
87 results