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Isocitrate dehydrogenase 1-mutated human gliomas depend on lactate and glutamate to alleviate metabolic stress.
Lenting K, Khurshed M, Peeters TH, van den Heuvel CNAM, van Lith SAM, de Bitter T, Hendriks W, Span PN, Molenaar RJ, Botman D, Verrijp K, Heerschap A, Ter Laan M, Kusters B, van Ewijk A, Huynen MA, van Noorden CJF, Leenders WPJ. Lenting K, et al. Among authors: de bitter t. FASEB J. 2019 Jan;33(1):557-571. doi: 10.1096/fj.201800907RR. Epub 2018 Jul 12. FASEB J. 2019. PMID: 30001166
The dependency on glutamate and lactate opens the way for novel approaches in the treatment of IDH(mut) gliomas.-Lenting, K., Khurshed, M., Peeters, T. H., van den Heuvel, C. N. A. M., van Lith, S. A. M., de Bitter, T., Hendriks, W., Span, P. ...
The dependency on glutamate and lactate opens the way for novel approaches in the treatment of IDH(mut) gliomas.-Lenting, K., Khurshed, M., …
Selective MET Kinase Inhibition in MET-Dependent Glioma Models Alters Gene Expression and Induces Tumor Plasticity.
van den Heuvel CNAM, Navis AC, de Bitter T, Amiri H, Verrijp K, Heerschap A, Rex K, Dussault I, Caenepeel S, Coxon A, Span PN, Wesseling P, Hendriks W, Leenders WPJ. van den Heuvel CNAM, et al. Among authors: de bitter t. Mol Cancer Res. 2017 Nov;15(11):1587-1597. doi: 10.1158/1541-7786.MCR-17-0177. Epub 2017 Jul 27. Mol Cancer Res. 2017. PMID: 28751462
Trends in Treatment and Survival of Gallbladder Cancer in the Netherlands; Identifying Gaps and Opportunities from a Nation-Wide Cohort.
de Savornin Lohman E, de Bitter T, Verhoeven R, van der Geest L, Hagendoorn J, Haj Mohammad N, Daams F, Klümpen HJ, van Gulik T, Erdmann J, de Boer M, Hoogwater F, Koerkamp BG, Braat A, Verheij J, Nagtegaal I, van Laarhoven C, van den Boezem P, van der Post R, de Reuver P. de Savornin Lohman E, et al. Among authors: de bitter t, de boer m, de reuver p. Cancers (Basel). 2020 Apr 9;12(4):918. doi: 10.3390/cancers12040918. Cancers (Basel). 2020. PMID: 32283627 Free PMC article.
Exploring the potential of circulating tumour DNA to monitor treatment response in salivary duct carcinoma patients of the CABO-ASAP trial.
Weijers JAM, de Bitter TJJ, Verhaegh GW, van Boxtel W, Uijen MJM, van Engen-van Grunsven ACH, Driessen CML, Schalken JA, Ligtenberg MJL, van Herpen CML. Weijers JAM, et al. Among authors: de bitter tjj. Oral Oncol. 2023 Dec;147:106620. doi: 10.1016/j.oraloncology.2023.106620. Epub 2023 Nov 6. Oral Oncol. 2023. PMID: 37939426 No abstract available.
Immunological and Genomic Analysis Reveals Clinically Relevant Distinctions between Angiosarcoma Subgroups.
van Ravensteijn SG, Versleijen-Jonkers YMH, Hillebrandt-Roeffen MHS, Weidema ME, Nederkoorn MJL, Bol KF, Gorris MAJ, Verrijp K, Kroeze LI, de Bitter TJJ, de Voer RM, Flucke UE, Desar IME. van Ravensteijn SG, et al. Among authors: de bitter tjj. Cancers (Basel). 2022 Nov 30;14(23):5938. doi: 10.3390/cancers14235938. Cancers (Basel). 2022. PMID: 36497420 Free PMC article.
Comprehensive clinicopathological and genomic profiling of gallbladder cancer reveals actionable targets in half of patients.
de Bitter TJJ, de Reuver PR, de Savornin Lohman EAJ, Kroeze LI, Vink-Börger ME, van Vliet S, Simmer F, von Rhein D, Jansen EAM, Verheij J, van Herpen CML, Nagtegaal ID, Ligtenberg MJL, van der Post RS. de Bitter TJJ, et al. NPJ Precis Oncol. 2022 Nov 5;6(1):83. doi: 10.1038/s41698-022-00327-y. NPJ Precis Oncol. 2022. PMID: 36335173 Free PMC article.
21 results