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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart.
Honkoop H, de Bakker DE, Aharonov A, Kruse F, Shakked A, Nguyen PD, de Heus C, Garric L, Muraro MJ, Shoffner A, Tessadori F, Peterson JC, Noort W, Bertozzi A, Weidinger G, Posthuma G, Grün D, van der Laarse WJ, Klumperman J, Jaspers RT, Poss KD, van Oudenaarden A, Tzahor E, Bakkers J. Honkoop H, et al. Among authors: de bakker de. Elife. 2019 Dec 23;8:e50163. doi: 10.7554/eLife.50163. Elife. 2019. PMID: 31868166 Free PMC article.
Conserved NPPB+ Border Zone Switches From MEF2- to AP-1-Driven Gene Program.
van Duijvenboden K, de Bakker DEM, Man JCK, Janssen R, Günthel M, Hill MC, Hooijkaas IB, van der Made I, van der Kraak PH, Vink A, Creemers EE, Martin JF, Barnett P, Bakkers J, Christoffels VM. van Duijvenboden K, et al. Among authors: de bakker dem. Circulation. 2019 Sep 9;140(10):864-879. doi: 10.1161/CIRCULATIONAHA.118.038944. Epub 2019 Jul 1. Circulation. 2019. PMID: 31259610
Zebrafish prrx1a mutants have normal hearts.
Tessadori F, de Bakker DEM, Barske L, Nelson N, Algra HA, Willekers S, Nichols JT, Crump JG, Bakkers J. Tessadori F, et al. Among authors: de bakker dem. Nature. 2020 Sep;585(7826):E14-E16. doi: 10.1038/s41586-020-2674-1. Epub 2020 Sep 23. Nature. 2020. PMID: 32968253 Free PMC article. No abstract available.
Cardiac regenerative capacity: an evolutionary afterthought?
Nguyen PD, de Bakker DEM, Bakkers J. Nguyen PD, et al. Among authors: de bakker dem. Cell Mol Life Sci. 2021 Jun;78(12):5107-5122. doi: 10.1007/s00018-021-03831-9. Epub 2021 May 5. Cell Mol Life Sci. 2021. PMID: 33950316 Free PMC article. Review.
Interplay between calcium and sarcomeres directs cardiomyocyte maturation during regeneration.
Nguyen PD, Gooijers I, Campostrini G, Verkerk AO, Honkoop H, Bouwman M, de Bakker DEM, Koopmans T, Vink A, Lamers GEM, Shakked A, Mars J, Mulder AA, Chocron S, Bartscherer K, Tzahor E, Mummery CL, de Boer TP, Bellin M, Bakkers J. Nguyen PD, et al. Among authors: de bakker dem. Science. 2023 May 19;380(6646):758-764. doi: 10.1126/science.abo6718. Epub 2023 May 18. Science. 2023. PMID: 37200435
Polyglucosan body density in the aged mouse hippocampus is controlled by a novel modifier locus on chromosome 1.
Gómez-Pascual A, Glikman DM, Ng HX, Tomkins JE, Lu L, Xu Y, Ashbrook DG, Kaczorowski C, Kempermann G, Killmar J, Mozhui K, Aebersold R, Williams EG, Williams RW, Overall RW, Jucker M, de Bakker DEM. Gómez-Pascual A, et al. Among authors: de bakker dem. bioRxiv [Preprint]. 2023 Nov 22:2023.11.22.567373. doi: 10.1101/2023.11.22.567373. bioRxiv. 2023. PMID: 38045339 Free PMC article. Preprint.