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Design, synthesis, and biological evaluation of new thalidomide-donepezil hybrids as neuroprotective agents targeting cholinesterases and neuroinflammation.
RSC Med Chem. 2022 Mar 17;13(5):568-584. doi: 10.1039/d1md00374g. eCollection 2022 May 25.
RSC Med Chem. 2022.
PMID: 35694691
Free PMC article.
Cinnamoyl-N-Acylhydrazone-Donepezil Hybrids: Synthesis and Evaluation of Novel Multifunctional Ligands Against Neurodegenerative Diseases.
Ortiz CJC, Damasio CM, Pruccoli L, Nadur NF, de Azevedo LL, Guedes IA, Dardenne LE, Kümmerle AE, Tarozzi A, Viegas C Jr.
Ortiz CJC, et al. Among authors: de azevedo ll.
Neurochem Res. 2020 Dec;45(12):3003-3020. doi: 10.1007/s11064-020-03148-2. Epub 2020 Oct 20.
Neurochem Res. 2020.
PMID: 33079324
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The long and winding road of designing phosphodiesterase inhibitors for the treatment of heart failure.
Nadur NF, de Azevedo LL, Caruso L, Graebin CS, Lacerda RB, Kümmerle AE.
Nadur NF, et al. Among authors: de azevedo ll.
Eur J Med Chem. 2021 Feb 15;212:113123. doi: 10.1016/j.ejmech.2020.113123. Epub 2020 Dec 24.
Eur J Med Chem. 2021.
PMID: 33412421
Review.
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Design, Synthesis and Biological Evaluation of Novel Triazole N-acylhydrazone Hybrids for Alzheimer's Disease.
de Freitas Silva M, Tardelli Lima E, Pruccoli L, Castro NG, Guimarães MJR, M R da Silva F, Fonseca Nadur N, de Azevedo LL, Kümmerle AE, Guedes IA, Dardenne LE, Gontijo VS, Tarozzi A, Viegas C.
de Freitas Silva M, et al. Among authors: de azevedo ll.
Molecules. 2020 Jul 10;25(14):3165. doi: 10.3390/molecules25143165.
Molecules. 2020.
PMID: 32664425
Free PMC article.
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