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MHTP, a synthetic tetratetrahydroisoquinoline alkaloid, attenuates lipopolysaccharide-induced acute lung injury via p38MAPK/p65NF-κB signaling pathway-TLR4 dependent.
do Nascimento Xavier BM, Ferreira LAMP, Ferreira LKDP, Gadelha FAAF, Monteiro TM, de Araújo Silva LA, Rodrigues LC, Piuvezam MR. do Nascimento Xavier BM, et al. Among authors: de araujo silva la. Inflamm Res. 2019 Dec;68(12):1061-1070. doi: 10.1007/s00011-019-01291-3. Epub 2019 Oct 17. Inflamm Res. 2019. PMID: 31624922
MHTP, 2-Methoxy-4-(7-methoxy-1,2,3,4-tetrahydroisoquinolin-1-yl) phenol, a Synthetic Alkaloid, Induces IFN-γ Production in Murine Model of Ovalbumin-Induced Pulmonary Allergic Inflammation.
Paiva Ferreira LKD, Paiva Ferreira LAM, Alves AF, Leite FC, de Araújo Silva LA, Vieira GC, Rodrigues LC, Piuvezam MR. Paiva Ferreira LKD, et al. Among authors: de araujo silva la. Inflammation. 2018 Dec;41(6):2116-2128. doi: 10.1007/s10753-018-0855-y. Inflammation. 2018. PMID: 30032472
MHTP, a synthetic alkaloid, attenuates combined allergic rhinitis and asthma syndrome through downregulation of the p38/ERK1/2 MAPK signaling pathway in mice.
Paiva Ferreira LKD, Paiva Ferreira LAM, Bezerra Barros GC, Mozzini Monteiro T, de Araújo Silva LA, Pereira RA, Figueiredo PTR, Alves AF, Rodrigues LC, Piuvezam MR. Paiva Ferreira LKD, et al. Among authors: de araujo silva la. Int Immunopharmacol. 2021 Jul;96:107590. doi: 10.1016/j.intimp.2021.107590. Epub 2021 Apr 13. Int Immunopharmacol. 2021. PMID: 33857802 Free article.