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Page 1
Antibacterial activity of lipophilic fluoroquinolone derivatives.
de Almeida CG, Diniz CG, Silva VL, Saraiva MF, Le Hyaric M, de Almeida MV. de Almeida CG, et al. Among authors: de almeida mv. Med Chem. 2009 Sep;5(5):419-21. doi: 10.2174/157340609789117859. Epub 2009 Sep 1. Med Chem. 2009. PMID: 19534679
Activity of pyrrolizidine alkaloids against biofilm formation and Trichomonas vaginalis.
da Silva Negreiros Neto T, Gardner D, Hallwass F, Leite AJM, de Almeida CG, Silva LN, de Araújo Roque A, de Bitencourt FG, Barbosa EG, Tasca T, Macedo AJ, de Almeida MV, Giordani RB. da Silva Negreiros Neto T, et al. Among authors: de almeida cg. Biomed Pharmacother. 2016 Oct;83:323-329. doi: 10.1016/j.biopha.2016.06.033. Epub 2016 Jul 9. Biomed Pharmacother. 2016. PMID: 27399809
Improved anti-Cutibacterium acnes activity of tea tree oil-loaded chitosan-poly(ε-caprolactone) core-shell nanocapsules.
da Silva NP, Carmo Rapozo Lavinas Pereira ED, Duarte LM, de Oliveira Freitas JC, de Almeida CG, da Silva TP, Melo RCN, Morais Apolônio AC, de Oliveira MAL, de Mello Brandão H, Pittella F, Fabri RL, Tavares GD, de Faria Pinto P. da Silva NP, et al. Among authors: de almeida cg. Colloids Surf B Biointerfaces. 2020 Dec;196:111371. doi: 10.1016/j.colsurfb.2020.111371. Epub 2020 Sep 19. Colloids Surf B Biointerfaces. 2020. PMID: 32980571
Optimization of a Novel Binding Motif to (E)-3-(3,5-Difluoro-4-((1R,3R)-2-(2-fluoro-2-methylpropyl)-3-methyl-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-yl)phenyl)acrylic Acid (AZD9496), a Potent and Orally Bioavailable Selective Estrogen Receptor Downregulator and Antagonist.
De Savi C, Bradbury RH, Rabow AA, Norman RA, de Almeida C, Andrews DM, Ballard P, Buttar D, Callis RJ, Currie GS, Curwen JO, Davies CD, Donald CS, Feron LJ, Gingell H, Glossop SC, Hayter BR, Hussain S, Karoutchi G, Lamont SG, MacFaul P, Moss TA, Pearson SE, Tonge M, Walker GE, Weir HM, Wilson Z. De Savi C, et al. J Med Chem. 2015 Oct 22;58(20):8128-40. doi: 10.1021/acs.jmedchem.5b00984. Epub 2015 Oct 7. J Med Chem. 2015. PMID: 26407012
AZD9496: An Oral Estrogen Receptor Inhibitor That Blocks the Growth of ER-Positive and ESR1-Mutant Breast Tumors in Preclinical Models.
Weir HM, Bradbury RH, Lawson M, Rabow AA, Buttar D, Callis RJ, Curwen JO, de Almeida C, Ballard P, Hulse M, Donald CS, Feron LJ, Karoutchi G, MacFaul P, Moss T, Norman RA, Pearson SE, Tonge M, Davies G, Walker GE, Wilson Z, Rowlinson R, Powell S, Sadler C, Richmond G, Ladd B, Pazolli E, Mazzola AM, D'Cruz C, De Savi C. Weir HM, et al. Cancer Res. 2016 Jun 1;76(11):3307-18. doi: 10.1158/0008-5472.CAN-15-2357. Epub 2016 Mar 28. Cancer Res. 2016. PMID: 27020862
The Identification of Potent, Selective, and Orally Available Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase: The Discovery of AZD0156 (8-{6-[3-(Dimethylamino)propoxy]pyridin-3-yl}-3-methyl-1-(tetrahydro-2 H-pyran-4-yl)-1,3-dihydro-2 H-imidazo[4,5- c]quinolin-2-one).
Pike KG, Barlaam B, Cadogan E, Campbell A, Chen Y, Colclough N, Davies NL, de-Almeida C, Degorce SL, Didelot M, Dishington A, Ducray R, Durant ST, Hassall LA, Holmes J, Hughes GD, MacFaul PA, Mulholland KR, McGuire TM, Ouvry G, Pass M, Robb G, Stratton N, Wang Z, Wilson J, Zhai B, Zhao K, Al-Huniti N. Pike KG, et al. J Med Chem. 2018 May 10;61(9):3823-3841. doi: 10.1021/acs.jmedchem.7b01896. Epub 2018 May 2. J Med Chem. 2018. PMID: 29683659
26 results