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Pharmacological inhibition of lysine-specific demethylase 1 (LSD1) induces global transcriptional deregulation and ultrastructural alterations that impair viability in Schistosoma mansoni.
Coutinho Carneiro V, de Abreu da Silva IC, Amaral MS, Pereira ASA, Silveira GO, Pires DDS, Verjovski-Almeida S, Dekker FJ, Rotili D, Mai A, Lopes-Torres EJ, Robaa D, Sippl W, Pierce RJ, Borrello MT, Ganesan A, Lancelot J, Thiengo S, Fernandez MA, Vicentino ARR, Mourão MM, Coelho FS, Fantappié MR. Coutinho Carneiro V, et al. Among authors: de abreu da silva ic. PLoS Negl Trop Dis. 2020 Jul 1;14(7):e0008332. doi: 10.1371/journal.pntd.0008332. eCollection 2020 Jul. PLoS Negl Trop Dis. 2020. PMID: 32609727 Free PMC article.
The dengue vector Aedes aegypti contains a functional high mobility group box 1 (HMGB1) protein with a unique regulatory C-terminus.
Ribeiro FS, de Abreu da Silva IC, Carneiro VC, Belgrano Fdos S, Mohana-Borges R, de Andrade Rosa I, Benchimol M, Souza NR, Mesquita RD, Sorgine MH, Gazos-Lopes F, Vicentino AR, Wu W, de Moraes Maciel R, da Silva-Neto MA, Fantappié MR. Ribeiro FS, et al. Among authors: de abreu da silva ic. PLoS One. 2012;7(7):e40192. doi: 10.1371/journal.pone.0040192. Epub 2012 Jul 3. PLoS One. 2012. PMID: 22802955 Free PMC article.
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