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In Vitro Schistosomicidal Activity of the Alkaloid-Rich Fraction from Ruta graveolens L. (Rutaceae) and Its Characterization by UPLC-QTOF-MS.
de Carvalho LSA, Queiroz LS, Alves Junior IJ, Almeida ADC, Coimbra ES, de Faria Pinto P, da Silva MPN, De Moraes J, Da Silva Filho AA. de Carvalho LSA, et al. Among authors: da silva mpn. Evid Based Complement Alternat Med. 2019 Nov 16;2019:7909137. doi: 10.1155/2019/7909137. eCollection 2019. Evid Based Complement Alternat Med. 2019. PMID: 31827562 Free PMC article.
Assessment of the In Vitro Antischistosomal Activities of the Extracts and Compounds from Solidago Microglossa DC (Asteraceae) and Aristolochia Cymbifera Mart. & Zucc. (Aristolochiaceae).
Costa PDS, Zuza da Silva OO, Costa DS, Silva LAO, de Faria Pinto P, da Silva MPN, de Moraes J, Da Silva Filho AA. Costa PDS, et al. Among authors: da silva mpn. Evid Based Complement Alternat Med. 2020 Sep 29;2020:1726365. doi: 10.1155/2020/1726365. eCollection 2020. Evid Based Complement Alternat Med. 2020. PMID: 33062001 Free PMC article.
Epiisopilosine alkaloid has activity against Schistosoma mansoni in mice without acute toxicity.
Guimarães MA, de Oliveira RN, de Almeida RL, Mafud AC, Sarkis ALV, Ganassin R, da Silva MP, Roquini DB, Veras LM, Sawada TCH, Ropke CD, Muehlmann LA, Joanitti GA, Kuckelhaus SAS, Allegretti SM, Mascarenhas YP, de Moraes J, Leite JRSA. Guimarães MA, et al. PLoS One. 2018 May 11;13(5):e0196667. doi: 10.1371/journal.pone.0196667. eCollection 2018. PLoS One. 2018. PMID: 29750792 Free PMC article.