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On the search for potential anti-Trypanosoma cruzi drugs: synthesis and biological evaluation of 2-hydroxy-3-methylamino and 1,2,3-triazolic naphthoquinoidal compounds obtained by click chemistry reactions.
da Silva Júnior EN, de Melo IM, Diogo EB, Costa VA, de Souza Filho JD, Valença WO, Camara CA, de Oliveira RN, de Araujo AS, Emery FS, dos Santos MR, de Simone CA, Menna-Barreto RF, de Castro SL. da Silva Júnior EN, et al. Eur J Med Chem. 2012 Jun;52:304-12. doi: 10.1016/j.ejmech.2012.03.039. Epub 2012 Mar 29. Eur J Med Chem. 2012. PMID: 22483633
Synthesis and anti-Trypanosoma cruzi activity of naphthoquinone-containing triazoles: electrochemical studies on the effects of the quinoidal moiety.
Diogo EB, Dias GG, Rodrigues BL, Guimarães TT, Valença WO, Camara CA, de Oliveira RN, da Silva MG, Ferreira VF, de Paiva YG, Goulart MO, Menna-Barreto RF, de Castro SL, da Silva Júnior EN. Diogo EB, et al. Among authors: da silva junior en, da silva mg. Bioorg Med Chem. 2013 Nov 1;21(21):6337-48. doi: 10.1016/j.bmc.2013.08.055. Epub 2013 Sep 6. Bioorg Med Chem. 2013. PMID: 24074878 Free article.
1,2,3-triazole-, arylamino- and thio-substituted 1,4-naphthoquinones: potent antitumor activity, electrochemical aspects, and bioisosteric replacement of C-ring-modified lapachones.
da Cruz EH, Hussene CM, Dias GG, Diogo EB, de Melo IM, Rodrigues BL, da Silva MG, Valença WO, Camara CA, de Oliveira RN, de Paiva YG, Goulart MO, Cavalcanti BC, Pessoa C, da Silva Júnior EN. da Cruz EH, et al. Among authors: da silva junior en, da silva mg. Bioorg Med Chem. 2014 Mar 1;22(5):1608-19. doi: 10.1016/j.bmc.2014.01.033. Epub 2014 Jan 31. Bioorg Med Chem. 2014. PMID: 24530030 Free article.
Novel fluorescent lapachone-based BODIPY: synthesis, computational and electrochemical aspects, and subcellular localisation of a potent antitumour hybrid quinone.
Gontijo TB, de Freitas RP, de Lima GF, de Rezende LC, Pedrosa LF, Silva TL, F Goulart MO, Cavalcanti BC, Pessoa C, Bruno MP, Corrêa JR, Emery FS, da Silva Júnior EN. Gontijo TB, et al. Among authors: da silva junior en, silva tl. Chem Commun (Camb). 2016 Nov 3;52(90):13281-13284. doi: 10.1039/c6cc07054j. Chem Commun (Camb). 2016. PMID: 27775736
84 results