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Anxiolytic- and antidepressant-like effects of new phenylpiperazine derivative LQFM005 and its hydroxylated metabolite in mice.
Moreira LKDS, Silva RR, da Silva DM, Mendes MAS, de Brito AF, de Carvalho FS, Sanz G, Rodrigues MF, da Silva ACG, Thomaz DV, de Oliveira V, Vaz BG, Lião LM, Valadares MC, Gil ES, Costa EA, Noël F, Menegatti R. Moreira LKDS, et al. Among authors: silva rr, da silva acg, da silva dm. Behav Brain Res. 2022 Jan 24;417:113582. doi: 10.1016/j.bbr.2021.113582. Epub 2021 Sep 15. Behav Brain Res. 2022. PMID: 34536431
Tert-butyl 4-((1-phenyl-1H-pyrazol-4-yl) methyl) piperazine-1-carboxylate (LQFM104)- New piperazine derivative with antianxiety and antidepressant-like effects: Putative role of serotonergic system.
da Silva DM, Sanz G, Vaz BG, de Carvalho FS, Lião LM, de Oliveira DR, Moreira LKDS, Cardoso CS, de Brito AF, da Silva DPB, da Rocha FF, Santana IGC, Galdino PM, Costa EA, Menegatti R. da Silva DM, et al. Among authors: da silva dpb, da rocha ff. Biomed Pharmacother. 2018 Jul;103:546-552. doi: 10.1016/j.biopha.2018.04.077. Epub 2018 Apr 24. Biomed Pharmacother. 2018. PMID: 29677541
Potential antidepressant-like effect of piperazine derivative LQFM212 in mice: Role of monoaminergic pathway and brain-derived neurotrophic factor.
Moreira LKDS, de Brito AF, da Silva DM, Siqueira L, da Silva DPB, Cardoso CS, Florentino IF, de Carvalho PMG, Ghedini PC, Menegatti R, Costa EA. Moreira LKDS, et al. Among authors: da silva dpb, da silva dm. Behav Brain Res. 2021 Mar 5;401:113066. doi: 10.1016/j.bbr.2020.113066. Epub 2020 Dec 14. Behav Brain Res. 2021. PMID: 33333109
Treatment of anxiety and depression: medicinal plants in retrospect.
Fajemiroye JO, da Silva DM, de Oliveira DR, Costa EA. Fajemiroye JO, et al. Among authors: da silva dm. Fundam Clin Pharmacol. 2016 Jun;30(3):198-215. doi: 10.1111/fcp.12186. Epub 2016 Mar 4. Fundam Clin Pharmacol. 2016. PMID: 26851117 Review.
Monoamine Involvement in the Antidepressant-Like Effect of β-Caryophyllene.
de Oliveira DR, da Silva DM, Florentino IF, de Brito AF, Fajemiroye JO, da Silva DPB, da Rocha FF, Costa EA, Galdino PM. de Oliveira DR, et al. Among authors: da silva dpb, da rocha ff, da silva dm. CNS Neurol Disord Drug Targets. 2018;17(4):309-320. doi: 10.2174/1871527317666180420150249. CNS Neurol Disord Drug Targets. 2018. PMID: 29676236
Pharmacological evaluation and molecular docking of new di-tert-butylphenol compound, LQFM-091, a new dual 5-LOX/COX inhibitor.
Lino RC, da Silva DPB, Florentino IF, da Silva DM, Martins JLR, Batista DDC, Leite KCS, Villavicencio B, Vasconcelos GA, Silva ALP, de Ávila RI, Verli H, Valadares MC, Gil ES, Vaz BG, Lião LM, Menegatti R, Costa EA. Lino RC, et al. Among authors: da silva dpb, da silva dm, silva alp. Eur J Pharm Sci. 2017 Aug 30;106:231-243. doi: 10.1016/j.ejps.2017.06.006. Eur J Pharm Sci. 2017. PMID: 28599988
Molecular docking and pharmacological/toxicological assessment of a new compound designed from celecoxib and paracetamol by molecular hybridization.
da Silva DPB, Florentino IF, da Silva DM, Lino RC, Cardoso CS, Moreira LKS, Vasconcelos GA, Vinhal DC, Cardoso ACD, Villavicencio B, Verli H, Vaz BG, Lião LM, da Cunha LC, Menegatti R, Costa EA. da Silva DPB, et al. Among authors: da cunha lc, da silva dm. Inflammopharmacology. 2018 Oct;26(5):1189-1206. doi: 10.1007/s10787-018-0516-7. Epub 2018 Jul 23. Inflammopharmacology. 2018. PMID: 30039481
187 results