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A partial agonist of PPARγ prevents paclitaxel-induced peripheral neuropathy in mice, by inhibiting neuroinflammation.
Benvenutti L, Wolff FR, Corrêa TP, Melato J, Goldoni FC, De Faveri R, Patel YBK, de Souza JA, Grockoski HA, Nilz PM, Bombardelli CL, Remor AP, Varela KG, Costa NTC, Hernandes MZ, Lacerda MG, Rodrigues KD, Milton FA, Neves FAR, Pereira MES, Kormann Imianowsky EC, de Campos Buzzi F, Brunaldi Marutani VH, Stoeberl LC, Correa R, Eller S, de Oliveira TF, Gonçalves TBP, da Silva RC, Passos GF, da Costa R, Santin JR, Quintão NLM. Benvenutti L, et al. Among authors: da silva rc, da costa r, costa ntc. Br J Pharmacol. 2024 Apr;181(7):1128-1149. doi: 10.1111/bph.16244. Epub 2023 Dec 1. Br J Pharmacol. 2024. PMID: 37721089
Mitotherapy prevents peripheral neuropathy induced by oxaliplatin in mice.
Maia JRLCB, Machado LKA, Fernandes GG, Vitorino LC, Antônio LS, Araújo SMB, Colodeti LC, Fontes-Dantas FL, Zeidler JD, Saraiva GN, Da Poian AT, Figueiredo CP, Passos GF, da Costa R. Maia JRLCB, et al. Among authors: da costa r, da poian at. Neuropharmacology. 2024 Mar 1;245:109828. doi: 10.1016/j.neuropharm.2023.109828. Epub 2023 Dec 27. Neuropharmacology. 2024. PMID: 38158014
P2X7 receptor contributes to long-term neuroinflammation and cognitive impairment in sepsis-surviving mice.
Alves VS, da Silva JP, Rodrigues FC, Araújo SMB, Gouvêa AL, Leite-Aguiar R, Santos SACS, da Silva MSP, Ferreira FS, Marques EP, Dos Passos BABR, Maron-Gutierrez T, Kurtenbach E, da Costa R, Figueiredo CP, Wyse ATS, Coutinho-Silva R, Savio LEB. Alves VS, et al. Among authors: da costa r, da silva jp, da silva msp. Front Pharmacol. 2023 Apr 21;14:1179723. doi: 10.3389/fphar.2023.1179723. eCollection 2023. Front Pharmacol. 2023. PMID: 37153798 Free PMC article.
SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice.
Fontes-Dantas FL, Fernandes GG, Gutman EG, De Lima EV, Antonio LS, Hammerle MB, Mota-Araujo HP, Colodeti LC, Araújo SMB, Froz GM, da Silva TN, Duarte LA, Salvio AL, Pires KL, Leon LAA, Vasconcelos CCF, Romão L, Savio LEB, Silva JL, da Costa R, Clarke JR, Da Poian AT, Alves-Leon SV, Passos GF, Figueiredo CP. Fontes-Dantas FL, et al. Among authors: da costa r, da poian at, da silva tn. Cell Rep. 2023 Mar 28;42(3):112189. doi: 10.1016/j.celrep.2023.112189. Epub 2023 Feb 17. Cell Rep. 2023. PMID: 36857178 Free PMC article.
Innate immune memory mediates increased susceptibility to Alzheimer's disease-like pathology in sepsis surviving mice.
De Sousa VL, Araújo SB, Antonio LM, Silva-Queiroz M, Colodeti LC, Soares C, Barros-Aragão F, Mota-Araujo HP, Alves VS, Coutinho-Silva R, Savio LEB, Ferreira ST, Da Costa R, Clarke JR, Figueiredo CP. De Sousa VL, et al. Among authors: da costa r. Brain Behav Immun. 2021 Jul;95:287-298. doi: 10.1016/j.bbi.2021.04.001. Epub 2021 Apr 8. Brain Behav Immun. 2021. PMID: 33838250
Cinnamaldehyde modulates LPS-induced systemic inflammatory response syndrome through TRPA1-dependent and independent mechanisms.
Mendes SJF, Sousa FIAB, Pereira DMS, Ferro TAF, Pereira ICP, Silva BLR, Pinheiro AJMCR, Mouchrek AQS, Monteiro-Neto V, Costa SKP, Nascimento JLM, Grisotto MAG, da Costa R, Fernandes ES. Mendes SJF, et al. Among authors: da costa r, costa skp. Int Immunopharmacol. 2016 May;34:60-70. doi: 10.1016/j.intimp.2016.02.012. Epub 2016 Feb 26. Int Immunopharmacol. 2016. PMID: 26922677 Free article.
Assessment of three antibiotic combination regimens against Gram-negative bacteria causing neonatal sepsis in low- and middle-income countries.
Kakaraskoska Boceska B, Vilken T, Xavier BB, Kostyanev T, Lin Q, Lammens C, Ellis S, O'Brien S, da Costa RMA, Cook A, Russell N, Bielicki J, Riddell A, Stohr W, Walker AS, Berezin EN, Roilides E, De Luca M, Romani L, Ballot D, Dramowski A, Wadula J, Lochindarat S, Boonkasidecha S, Namiiro F, Ngoc HTB, Tran MD, Cressey TR, Preedisripipat K, Berkley JA, Musyimi R, Zarras C, Nana T, Whitelaw A, da Silva CB, Jaglal P, Ssengooba W, Saha SK, Islam MS, Mussi-Pinhata MM, Carvalheiro CG, Piddock LJV, Heath PT, Malhotra-Kumar S, Sharland M, Glupczynski Y, Goossens H. Kakaraskoska Boceska B, et al. Among authors: da costa rma. Nat Commun. 2024 May 10;15(1):3947. doi: 10.1038/s41467-024-48296-z. Nat Commun. 2024. PMID: 38729951 Free PMC article.
630 results