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Native and bioengineered extracellular vesicles for cardiovascular therapeutics.
de Abreu RC, Fernandes H, da Costa Martins PA, Sahoo S, Emanueli C, Ferreira L. de Abreu RC, et al. Among authors: da costa martins pa. Nat Rev Cardiol. 2020 Nov;17(11):685-697. doi: 10.1038/s41569-020-0389-5. Epub 2020 Jun 1. Nat Rev Cardiol. 2020. PMID: 32483304 Free PMC article. Review.
A microRNA program regulates the balance between cardiomyocyte hyperplasia and hypertrophy and stimulates cardiac regeneration.
Raso A, Dirkx E, Sampaio-Pinto V, El Azzouzi H, Cubero RJ, Sorensen DW, Ottaviani L, Olieslagers S, Huibers MM, de Weger R, Siddiqi S, Moimas S, Torrini C, Zentillin L, Braga L, Nascimento DS, da Costa Martins PA, van Berlo JH, Zacchigna S, Giacca M, De Windt LJ. Raso A, et al. Among authors: da costa martins pa. Nat Commun. 2021 Aug 10;12(1):4808. doi: 10.1038/s41467-021-25211-4. Nat Commun. 2021. PMID: 34376683 Free PMC article.
Exogenous loading of miRNAs into small extracellular vesicles.
de Abreu RC, Ramos CV, Becher C, Lino M, Jesus C, da Costa Martins PA, Martins PAT, Moreno MJ, Fernandes H, Ferreira L. de Abreu RC, et al. Among authors: da costa martins pa. J Extracell Vesicles. 2021 Aug;10(10):e12111. doi: 10.1002/jev2.12111. Epub 2021 Aug 2. J Extracell Vesicles. 2021. PMID: 34377372 Free PMC article.
Intercellular transfer of miR-200c-3p impairs the angiogenic capacity of cardiac endothelial cells.
Ottaviani L, Juni RP, de Abreu RC, Sansonetti M, Sampaio-Pinto V, Halkein J, Hegenbarth JC, Ring N, Knoops K, Kocken JMM, Jesus C, Ernault AC, El Azzouzi H, Rühle F, Olieslagers S, Fernandes H, Ferreira L, Braga L, Stoll M, Nascimento DS, de Windt LJ, da Costa Martins PA. Ottaviani L, et al. Among authors: da costa martins pa. Mol Ther. 2022 Jun 1;30(6):2257-2273. doi: 10.1016/j.ymthe.2022.03.002. Epub 2022 Mar 9. Mol Ther. 2022. PMID: 35278675 Free PMC article.
Extracellular vesicles enriched with an endothelial cell pro-survival microRNA affects skin tissue regeneration.
Fernandes H, Zonnari A, Abreu R, Aday S, Barão M, Albino I, Lino M, Branco A, Seabra C, Barata T, Leal EC, Tralhão JG, Gonçalves L, de Jong A, Peters HAB, de Vries MR, da Costa Martins P, Quax PHA, Ferreira L. Fernandes H, et al. Mol Ther Nucleic Acids. 2022 Mar 19;28:307-327. doi: 10.1016/j.omtn.2022.03.018. eCollection 2022 Jun 14. Mol Ther Nucleic Acids. 2022. PMID: 35474734 Free PMC article.
MicroRNA regulation in cardiovascular disease.
da Costa Martins PA, Leptidis S, Salic K, De Windt LJ. da Costa Martins PA, et al. Curr Drug Targets. 2010 Aug;11(8):900-6. doi: 10.2174/138945010791591322. Curr Drug Targets. 2010. PMID: 20415652 Review.
MicroRNAs in control of cardiac hypertrophy.
Da Costa Martins PA, De Windt LJ. Da Costa Martins PA, et al. Cardiovasc Res. 2012 Mar 15;93(4):563-72. doi: 10.1093/cvr/cvs013. Epub 2012 Jan 19. Cardiovasc Res. 2012. PMID: 22266752 Review.
Antisense MicroRNA Therapeutics in Cardiovascular Disease: Quo Vadis?
Philippen LE, Dirkx E, Wit JB, Burggraaf K, de Windt LJ, da Costa Martins PA. Philippen LE, et al. Among authors: da costa martins pa. Mol Ther. 2015 Dec;23(12):1810-8. doi: 10.1038/mt.2015.133. Epub 2015 Jul 28. Mol Ther. 2015. PMID: 26216517 Free PMC article. Review.
74 results