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Hepatoblastomas exhibit marked NNMT downregulation driven by promoter DNA hypermethylation.
Rivas MP, Aguiar TFM, Maschietto M, Lemes RB, Caires-Júnior LC, Goulart E, Telles-Silva KA, Novak E, Cristofani LM, Odone V, Cypriano M, de Toledo SRC, Carraro DM, Escobar MQ, Lee H, Johnston M, da Costa CML, da Cunha IW, Tasic L, Pearson PL, Rosenberg C, Timchenko N, Krepischi ACV. Rivas MP, et al. Among authors: da costa cml. Tumour Biol. 2020 Dec;42(12):1010428320977124. doi: 10.1177/1010428320977124. Tumour Biol. 2020. PMID: 33256542 Free article.
DNA methylation landscape of hepatoblastomas reveals arrest at early stages of liver differentiation and cancer-related alterations.
Maschietto M, Rodrigues TC, Kashiwabara AY, de Araujo ÉSS, Marques Aguiar TF, da Costa CML, da Cunha IW, Dos Reis Vasques L, Cypriano M, Brentani H, de Toledo SRC, Pearson PL, Carraro DM, Rosenberg C, Krepischi ACV. Maschietto M, et al. Among authors: da costa cml. Oncotarget. 2016 Dec 25;8(58):97871-97889. doi: 10.18632/oncotarget.14208. eCollection 2017 Nov 17. Oncotarget. 2016. PMID: 29228658 Free PMC article.
TET Upregulation Leads to 5-Hydroxymethylation Enrichment in Hepatoblastoma.
Rivas MP, Aguiar TFM, Fernandes GR, Caires-Júnior LC, Goulart E, Telles-Silva KA, Cypriano M, de Toledo SRC, Rosenberg C, Carraro DM, da Costa CML, da Cunha IW, Krepischi ACV. Rivas MP, et al. Among authors: da costa cml. Front Genet. 2019 Jun 12;10:553. doi: 10.3389/fgene.2019.00553. eCollection 2019. Front Genet. 2019. PMID: 31249594 Free PMC article.
DNA methylation as a key epigenetic player for hepatoblastoma characterization.
Rivas M, Aguiar T, Fernandes G, Lemes R, Caires-Júnior L, Goulart E, Telles-Silva K, Maschietto M, Cypriano M, de Toledo S, Carraro D, da Cunha I, da Costa C, Rosenberg C, Krepischi A. Rivas M, et al. Clin Res Hepatol Gastroenterol. 2021 May;45(3):101684. doi: 10.1016/j.clinre.2021.101684. Epub 2021 Apr 20. Clin Res Hepatol Gastroenterol. 2021. PMID: 33852955
First Transcriptome Analysis of Hepatoblastoma in Brazil: Unraveling the Pivotal Role of Noncoding RNAs and Metabolic Pathways.
Aguiar TFM, Rivas MP, de Andrade Silva EM, Pires SF, Dangoni GD, Macedo TC, Defelicibus A, Barros BDF, Novak E, Cristofani LM, Odone V, Cypriano M, de Toledo SRC, da Cunha IW, da Costa CML, Carraro DM, Tojal I, de Oliveira Mendes TA, Krepischi ACV. Aguiar TFM, et al. Among authors: da costa cml. Biochem Genet. 2024 Apr 22. doi: 10.1007/s10528-024-10764-y. Online ahead of print. Biochem Genet. 2024. PMID: 38649558
Assessment of somatic mutations in urine and plasma of Wilms tumor patients.
Miguez ACK, Barros BDF, de Souza JES, da Costa CML, Cunha IW, Barbosa PNVP, Apezzato MLP, de Souza SJ, Carraro DM. Miguez ACK, et al. Among authors: da costa cml. Cancer Med. 2020 Aug;9(16):5948-5959. doi: 10.1002/cam4.3236. Epub 2020 Jun 26. Cancer Med. 2020. PMID: 32592321 Free PMC article.
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