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Page 1
Amyloid Beta and Tau Cooperate to Cause Reversible Behavioral and Transcriptional Deficits in a Model of Alzheimer's Disease.
Pickett EK, Herrmann AG, McQueen J, Abt K, Dando O, Tulloch J, Jain P, Dunnett S, Sohrabi S, Fjeldstad MP, Calkin W, Murison L, Jackson RJ, Tzioras M, Stevenson A, d'Orange M, Hooley M, Davies C, Colom-Cadena M, Anton-Fernandez A, King D, Oren I, Rose J, McKenzie CA, Allison E, Smith C, Hardt O, Henstridge CM, Hardingham GE, Spires-Jones TL. Pickett EK, et al. Among authors: d orange m. Cell Rep. 2019 Dec 10;29(11):3592-3604.e5. doi: 10.1016/j.celrep.2019.11.044. Cell Rep. 2019. PMID: 31825838 Free PMC article.
Neuronal tau species transfer to astrocytes and induce their loss according to tau aggregation state.
Maté de Gérando A, d'Orange M, Augustin E, Joséphine C, Aurégan G, Gaudin-Guérif M, Guillermier M, Hérard AS, Stimmer L, Petit F, Gipchtein P, Jan C, Escartin C, Selingue E, Carvalho K, Blum D, Brouillet E, Hantraye P, Gaillard MC, Bonvento G, Bemelmans AP, Cambon K. Maté de Gérando A, et al. Among authors: d orange m. Brain. 2021 May 7;144(4):1167-1182. doi: 10.1093/brain/awab011. Brain. 2021. PMID: 33842937
Potentiating tangle formation reduces acute toxicity of soluble tau species in the rat.
d'Orange M, Aurégan G, Cheramy D, Gaudin-Guérif M, Lieger S, Guillermier M, Stimmer L, Joséphine C, Hérard AS, Gaillard MC, Petit F, Kiessling MC, Schmitz C, Colin M, Buée L, Panayi F, Diguet E, Brouillet E, Hantraye P, Bemelmans AP, Cambon K. d'Orange M, et al. Brain. 2018 Feb 1;141(2):535-549. doi: 10.1093/brain/awx342. Brain. 2018. PMID: 29253129 Free PMC article.
Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy.
Lentini C, d'Orange M, Marichal N, Trottmann MM, Vignoles R, Foucault L, Verrier C, Massera C, Raineteau O, Conzelmann KK, Rival-Gervier S, Depaulis A, Berninger B, Heinrich C. Lentini C, et al. Among authors: d orange m. Cell Stem Cell. 2021 Dec 2;28(12):2104-2121.e10. doi: 10.1016/j.stem.2021.09.002. Epub 2021 Sep 29. Cell Stem Cell. 2021. PMID: 34592167 Free PMC article.