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Page 1
Central inhibition of stearoyl-CoA desaturase has minimal effects on the peripheral metabolic symptoms of the 3xTg Alzheimer's disease mouse model.
Hamilton LK, M'Bra PEH, Mailloux S, Galoppin M, Aumont A, Fernandes KJL. Hamilton LK, et al. Sci Rep. 2024 Apr 2;14(1):7742. doi: 10.1038/s41598-024-58272-8. Sci Rep. 2024. PMID: 38565895 Free PMC article.
Evidence from genetic and epidemiological studies point to lipid metabolism defects in both the brain and periphery being at the core of Alzheimer's disease (AD) pathogenesis. ...Given the widespread side-effects of systemically administered SCD inhibitors, these data sugg …
Evidence from genetic and epidemiological studies point to lipid metabolism defects in both the brain and periphery being at the core …
Examining the latent structure and correlates of sensory reactivity in autism: a multi-site integrative data analysis by the autism sensory research consortium.
Williams ZJ, Schaaf R, Ausderau KK, Baranek GT, Barrett DJ, Cascio CJ, Dumont RL, Eyoh EE, Failla MD, Feldman JI, Foss-Feig JH, Green HL, Green SA, He JL, Kaplan-Kahn EA, Keçeli-Kaysılı B, MacLennan K, Mailloux Z, Marco EJ, Mash LE, McKernan EP, Molholm S, Mostofsky SH, Puts NAJ, Robertson CE, Russo N, Shea N, Sideris J, Sutcliffe JS, Tavassoli T, Wallace MT, Wodka EL, Woynaroski TG. Williams ZJ, et al. Mol Autism. 2023 Aug 28;14(1):31. doi: 10.1186/s13229-023-00563-4. Mol Autism. 2023. PMID: 37635263 Free PMC article.
Quality Indicators Targeting Low-Value Clinical Practices in Trauma Care.
Moore L, Bérubé M, Tardif PA, Lauzier F, Turgeon A, Cameron P, Champion H, Yanchar N, Lecky F, Kortbeek J, Evans D, Mercier É, Archambault P, Lamontagne F, Gabbe B, Paquet J, Razek T, Stelfox HT; Low-Value Practices in Trauma Care Expert Consensus Group. Moore L, et al. JAMA Surg. 2022 Jun 1;157(6):507-514. doi: 10.1001/jamasurg.2022.0812. JAMA Surg. 2022. PMID: 35476055 Free PMC article.
Selected indicators targeted low-value clinical practices in the following aspects of trauma care: (1) initial diagnostic imaging (head, cervical spine, ankle, and pelvis), (2) repeated diagnostic imaging (posttransfer computed tomography [CT] and repeated head CT), (3) consultat …
Selected indicators targeted low-value clinical practices in the following aspects of trauma care: (1) initial diagnostic imaging (head, cer …
Dexmedetomidine or Propofol for Sedation in Mechanically Ventilated Adults with Sepsis.
Hughes CG, Mailloux PT, Devlin JW, Swan JT, Sanders RD, Anzueto A, Jackson JC, Hoskins AS, Pun BT, Orun OM, Raman R, Stollings JL, Kiehl AL, Duprey MS, Bui LN, O'Neal HR Jr, Snyder A, Gropper MA, Guntupalli KK, Stashenko GJ, Patel MB, Brummel NE, Girard TD, Dittus RS, Bernard GR, Ely EW, Pandharipande PP; MENDS2 Study Investigators. Hughes CG, et al. N Engl J Med. 2021 Apr 15;384(15):1424-1436. doi: 10.1056/NEJMoa2024922. Epub 2021 Feb 2. N Engl J Med. 2021. PMID: 33528922 Free PMC article. Clinical Trial.
Cereblon harnesses Myc-dependent bioenergetics and activity of CD8+ T lymphocytes.
Hesterberg RS, Beatty MS, Han Y, Fernandez MR, Akuffo AA, Goodheart WE, Yang C, Chang S, Colin CM, Alontaga AY, McDaniel JM, Mailloux AW, Billington JMR, Yue L, Russell S, Gillies RJ, Yun SY, Ayaz M, Lawrence NJ, Lawrence HR, Yu XZ, Fu J, Darville LN, Koomen JM, Ren X, Messina J, Jiang K, Garrett TJ, Rajadhyaksha AM, Cleveland JL, Epling-Burnette PK. Hesterberg RS, et al. Blood. 2020 Aug 13;136(7):857-870. doi: 10.1182/blood.2019003257. Blood. 2020. PMID: 32403132 Free PMC article.
Guidelines for the Acute Treatment of Cerebral Edema in Neurocritical Care Patients.
Cook AM, Morgan Jones G, Hawryluk GWJ, Mailloux P, McLaughlin D, Papangelou A, Samuel S, Tokumaru S, Venkatasubramanian C, Zacko C, Zimmermann LL, Hirsch K, Shutter L. Cook AM, et al. Neurocrit Care. 2020 Jun;32(3):647-666. doi: 10.1007/s12028-020-00959-7. Neurocrit Care. 2020. PMID: 32227294 Free PMC article.
RESULTS: The panel generated recommendations regarding initial management of cerebral edema in neurocritical care patients with subarachnoid hemorrhage, traumatic brain injury, acute ischemic stroke, intracerebral hemorrhage, bacterial meningitis, and hepatic encephalopath …
RESULTS: The panel generated recommendations regarding initial management of cerebral edema in neurocritical care patients with subarachnoid …
Neural Foundations of Ayres Sensory Integration®.
Lane SJ, Mailloux Z, Schoen S, Bundy A, May-Benson TA, Parham LD, Smith Roley S, Schaaf RC. Lane SJ, et al. Brain Sci. 2019 Jun 28;9(7):153. doi: 10.3390/brainsci9070153. Brain Sci. 2019. PMID: 31261689 Free PMC article.
The Effects of Experimental Manipulation of Sleep Duration on Neural Response to Food Cues.
Demos KE, Sweet LH, Hart CN, McCaffery JM, Williams SE, Mailloux KA, Trautvetter J, Owens MM, Wing RR. Demos KE, et al. Sleep. 2017 Nov 1;40(11):zsx125. doi: 10.1093/sleep/zsx125. Sleep. 2017. PMID: 28977574 Free PMC article. Clinical Trial.
Despite growing literature on neural food cue responsivity in obesity, little is known about how the brain processes food cues following partial sleep deprivation and whether short sleep leads to changes similar to those observed in obesity. ...Following each sleep conditi …
Despite growing literature on neural food cue responsivity in obesity, little is known about how the brain processes food cues follow …
Superoxide anion radical (O2(-)) degrades methylmercury to inorganic mercury in human astrocytoma cell line (CCF-STTG1).
Mailloux RJ, Yumvihoze E, Chan HM. Mailloux RJ, et al. Chem Biol Interact. 2015 Sep 5;239:46-55. doi: 10.1016/j.cbi.2015.06.028. Epub 2015 Jun 22. Chem Biol Interact. 2015. PMID: 26111762
It has been known for some time that MeHg can be progressively converted to inorganic mercury (iHg) in various tissues including the brain. Recent work has suggested that cleavage of the carbon-metal bond in MeHg in a biological environment is facilitated by reactive oxyge …
It has been known for some time that MeHg can be progressively converted to inorganic mercury (iHg) in various tissues including the brai …
25 results