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2014 1
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34 results

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TFEB ameliorates DEHP-induced neurotoxicity by activating GAL3/TRIM16 axis dependent lysophagy and alleviating lysosomal dysfunction.
Xing H, Xu P, Ma Y, Li T, Zhang Y, Ding X, Liu L, Keerman M, Niu Q. Xing H, et al. Environ Toxicol. 2024 Mar 15. doi: 10.1002/tox.24221. Online ahead of print. Environ Toxicol. 2024. PMID: 38488668
Taken together, our findings highlight the critical role of TFEB in regulating lysophagy and lysosomal function. Furthermore, TFEB may serve as a potential therapeutic target for mitigating DEHP-induced neuronal toxicity....
Taken together, our findings highlight the critical role of TFEB in regulating lysophagy and lysosomal function. Furthermore, TFEB may serve …
Effect of sunitinib against Echinococcus multilocularis through inhibition of VEGFA-induced angiogenesis.
Jiang H, Wang X, Guo L, Tan X, Gui X, Liao Z, Li Z, Chen X, Wu X. Jiang H, et al. Parasit Vectors. 2023 Nov 7;16(1):407. doi: 10.1186/s13071-023-05999-4. Parasit Vectors. 2023. PMID: 37936208 Free PMC article.
BACKGROUND: Alveolar echinococcosis (AE) is a lethal zoonosis caused by the fox tapeworm Echinococcus multilocularis. The disease is difficult to treat, and an effective therapeutic drug is urgently needed. Echinococcus multilocularis-associated angiogenesis is required by …
BACKGROUND: Alveolar echinococcosis (AE) is a lethal zoonosis caused by the fox tapeworm Echinococcus multilocularis. The disease is difficu …
A Potential Driver of Disseminated Intravascular Coagulation in Heat Stroke Mice: Neutrophil Extracellular Traps.
Zhang Y, Deng X, Zhang J, Zhang L, Akram Z, Zhang B, Sun S. Zhang Y, et al. Int J Environ Res Public Health. 2022 Sep 29;19(19):12448. doi: 10.3390/ijerph191912448. Int J Environ Res Public Health. 2022. PMID: 36231751 Free PMC article.
These results indicate that NETs may hold potential alternative therapeutic strategies for the treatment of DIC in HS patients....
These results indicate that NETs may hold potential alternative therapeutic strategies for the treatment of DIC in HS patients....
One-pot fabrication of a polydopamine-based nanoplatform for GSH triggered trimodal ROS-amplification for cancer therapy.
Wang Q, Jia X, Li X, He M, Hao JN, Guan M, Mao Y, Cao Y, Dai B, Li Y. Wang Q, et al. Biomater Sci. 2022 Jul 26;10(15):4208-4217. doi: 10.1039/d2bm00421f. Biomater Sci. 2022. PMID: 35734909
However, the activated endogenous antioxidant defense of cancer cells in response to the ROS attack greatly hinders their therapeutic efficacy. Although cancer-specific ROS amplification strategies have been widely explored, most of them suffer from tedious synthesis proce …
However, the activated endogenous antioxidant defense of cancer cells in response to the ROS attack greatly hinders their therapeutic
Long circulation and tumor-targeting biomimetic nanoparticles for efficient chemo/photothermal synergistic therapy.
Zhang Y, Yue X, Yang S, Li X, Cui L, Cui X, Shi Y, Liu Z, Guo X, Li Y. Zhang Y, et al. J Mater Chem B. 2022 Jul 6;10(26):5035-5044. doi: 10.1039/d2tb00748g. J Mater Chem B. 2022. PMID: 35726686
Photothermal therapy combined with chemotherapy based on nanomedicine has been considered a promising strategy for improving therapeutic efficacy in a tumor. However, nanomedicine can be easily cleared by the immune system without specific surface engineering modifications …
Photothermal therapy combined with chemotherapy based on nanomedicine has been considered a promising strategy for improving therapeutic
Interfacial-confined coordination to single-atom nanotherapeutics.
Qin L, Gan J, Niu D, Cao Y, Duan X, Qin X, Zhang H, Jiang Z, Jiang Y, Dai S, Li Y, Shi J. Qin L, et al. Nat Commun. 2022 Jan 10;13(1):91. doi: 10.1038/s41467-021-27640-7. Nat Commun. 2022. PMID: 35013181 Free PMC article.
The present methodology provides a scientific paradigm to design and develop versatile single atom nanotherapeutics with adjustable metal components and tune the corresponding reactions for safe and efficient tumor therapeutic strategy....
The present methodology provides a scientific paradigm to design and develop versatile single atom nanotherapeutics with adjustable metal co …
34 results