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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1969 1
1974 1
1975 3
1976 1
1979 1
1980 2
1981 2
1982 7
1983 5
1984 7
1985 7
1986 5
1987 14
1988 14
1989 27
1990 26
1991 26
1992 47
1993 56
1994 69
1995 53
1996 64
1997 77
1998 75
1999 78
2000 66
2001 76
2002 89
2003 90
2004 115
2005 124
2006 131
2007 143
2008 174
2009 152
2010 159
2011 170
2012 214
2013 202
2014 232
2015 257
2016 242
2017 280
2018 291
2019 316
2020 362
2021 429
2022 529
2023 486
2024 203

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5,589 results

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Page 1
Anti-PEG antibodies: Properties, formation, testing and role in adverse immune reactions to PEGylated nano-biopharmaceuticals.
Kozma GT, Shimizu T, Ishida T, Szebeni J. Kozma GT, et al. Adv Drug Deliv Rev. 2020;154-155:163-175. doi: 10.1016/j.addr.2020.07.024. Epub 2020 Aug 1. Adv Drug Deliv Rev. 2020. PMID: 32745496 Free article. Review.
Nevertheless, these drugs and agents are often immunogenic, triggering the rise of anti-drug antibodies (ADAs). Among these ADAs, anti-PEG IgG and IgM were shown to account for efficacy loss due to accelerated blood clearance of the drug (ABC phenomenon) and …
Nevertheless, these drugs and agents are often immunogenic, triggering the rise of anti-drug antibodies (ADAs). Among these AD …
Autoimmune Encephalitis: Current Knowledge on Subtypes, Disease Mechanisms and Treatment.
Nissen MS, Ryding M, Meyer M, Blaabjerg M. Nissen MS, et al. CNS Neurol Disord Drug Targets. 2020;19(8):584-598. doi: 10.2174/1871527319666200708133103. CNS Neurol Disord Drug Targets. 2020. PMID: 32640967 Review.
Autoimmune Encephalitides (AE) comprises a group of diseases with antibodies against neuronal synaptic and cell surface antigens. Since the discovery of the most common subtype, NMethyl- D-Aspartate (NMDA) receptor encephalitis, an astonishing number of novel disease-causi …
Autoimmune Encephalitides (AE) comprises a group of diseases with antibodies against neuronal synaptic and cell surface antigens. Sin …
Anti-Hu antibodies activate enteric and sensory neurons.
Li Q, Michel K, Annahazi A, Demir IE, Ceyhan GO, Zeller F, Komorowski L, Stöcker W, Beyak MJ, Grundy D, Farrugia G, De Giorgio R, Schemann M. Li Q, et al. Sci Rep. 2016 Dec 1;6:38216. doi: 10.1038/srep38216. Sci Rep. 2016. PMID: 27905561 Free PMC article.
IgG of type 1 anti-neuronal nuclear antibody (ANNA-1, anti-Hu) specificity is a serological marker of paraneoplastic neurological autoimmunity (including enteric/autonomic) usually related to small-cell lung carcinoma. ...The results provide evidence f …
IgG of type 1 anti-neuronal nuclear antibody (ANNA-1, anti-Hu) specificity is a serological marker of paraneopla …
Anti-IgLON5 antibodies cause progressive behavioral and neuropathological changes in mice.
Ni Y, Feng Y, Shen D, Chen M, Zhu X, Zhou Q, Gao Y, Liu J, Zhang Q, Shen Y, Peng L, Zeng Z, Yin D, Hu J, Chen S. Ni Y, et al. J Neuroinflammation. 2022 Jun 11;19(1):140. doi: 10.1186/s12974-022-02520-z. J Neuroinflammation. 2022. PMID: 35690819 Free PMC article.
METHODS: We investigated the effects of anti-IgLON5 antibodies in vivo and evaluated their long-term effects. ...Microglial and astrocyte density was increased in the hippocampus of anti-IgLON5 IgG-injected mice at Day 30. Whole-cell voltage clamp recordings …
METHODS: We investigated the effects of anti-IgLON5 antibodies in vivo and evaluated their long-term effects. ...Microglial an …
Structure-based engineering of a novel CD3epsilon-targeting antibody for reduced polyreactivity.
Liu CY, Ahonen CL, Brown ME, Zhou L, Welin M, Krauland EM, Pejchal R, Widboom PF, Battles MB. Liu CY, et al. MAbs. 2023 Jan-Dec;15(1):2189974. doi: 10.1080/19420862.2023.2189974. MAbs. 2023. PMID: 36991534 Free PMC article.
Bispecific antibodies continue to represent a growth area for antibody therapeutics, with roughly a third of molecules in clinical development being T-cell engagers that use an anti-CD3 binding arm. ...Using insights from the crystal structure of anti- …
Bispecific antibodies continue to represent a growth area for antibody therapeutics, with roughly a third of molecules in clin …
Intrathecal synthesis of anti-Hu antibodies distinguishes patients with paraneoplastic peripheral neuropathy and encephalitis.
Schwenkenbecher P, Chacko LP, Wurster U, Pars K, Pul R, Sühs KW, Stangel M, Skripuletz T. Schwenkenbecher P, et al. BMC Neurol. 2016 Aug 11;16(1):136. doi: 10.1186/s12883-016-0657-5. BMC Neurol. 2016. PMID: 27515847 Free PMC article.
METHODS: We retrospectively evaluated data of 18 patients with paraneoplastic syndromes due to anti-Hu antibodies. The study aimed to differentiate patients with peripheral neuropathy and encephalitis by cerebrospinal fluid (CSF) parameters including anti
METHODS: We retrospectively evaluated data of 18 patients with paraneoplastic syndromes due to anti-Hu antibodies. The …
Endocytosis Inhibition in Humans to Improve Responses to ADCC-Mediating Antibodies.
Chew HY, De Lima PO, Gonzalez Cruz JL, Banushi B, Echejoh G, Hu L, Joseph SR, Lum B, Rae J, O'Donnell JS, Merida de Long L, Okano S, King B, Barry R, Moi D, Mazzieri R, Thomas R, Souza-Fonseca-Guimaraes F, Foote M, McCluskey A, Robinson PJ, Frazer IH, Saunders NA, Parton RG, Dolcetti R, Cuff K, Martin JH, Panizza B, Walpole E, Wells JW, Simpson F. Chew HY, et al. Cell. 2020 Mar 5;180(5):895-914.e27. doi: 10.1016/j.cell.2020.02.019. Cell. 2020. PMID: 32142680 Free article.
A safe and controlled manipulation of endocytosis in vivo may have disruptive therapeutic potential. Here, we demonstrate that the anti-emetic/anti-psychotic prochlorperazine can be repurposed to reversibly inhibit the in vivo endocytosis of membrane proteins target …
A safe and controlled manipulation of endocytosis in vivo may have disruptive therapeutic potential. Here, we demonstrate that the anti
BRCA1 Antibodies Matter.
Yang J, Qi L, Chiang HC, Yuan B, Li R, Hu Y. Yang J, et al. Int J Biol Sci. 2021 Jul 25;17(12):3239-3254. doi: 10.7150/ijbs.63115. eCollection 2021. Int J Biol Sci. 2021. PMID: 34421362 Free PMC article.
In search of reliable and specific BRCA1 antibodies (Abs), particularly antibodies recognizing mouse BRCA1, we performed a rigorous validation of a number of commercially available anti-BRCA1 antibodies, using proper controls in a panel of validation a …
In search of reliable and specific BRCA1 antibodies (Abs), particularly antibodies recognizing mouse BRCA1, we performed a rig …
5,589 results