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Page 1
Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis.
Kwok AJ, Allcock A, Ferreira RC, Cano-Gamez E, Smee M, Burnham KL, Zurke YX; Emergency Medicine Research Oxford (EMROx); McKechnie S, Mentzer AJ, Monaco C, Udalova IA, Hinds CJ, Todd JA, Davenport EE, Knight JC. Kwok AJ, et al. Among authors: zurke yx. Nat Immunol. 2023 May;24(5):767-779. doi: 10.1038/s41590-023-01490-5. Epub 2023 Apr 24. Nat Immunol. 2023. PMID: 37095375
Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19.
Kotanidis CP, Xie C, Alexander D, Rodrigues JCL, Burnham K, Mentzer A, O'Connor D, Knight J, Siddique M, Lockstone H, Thomas S, Kotronias R, Oikonomou EK, Badi I, Lyasheva M, Shirodaria C, Lumley SF, Constantinides B, Sanderson N, Rodger G, Chau KK, Lodge A, Tsakok M, Gleeson F, Adlam D, Rao P, Indrajeet D, Deshpande A, Bajaj A, Hudson BJ, Srivastava V, Farid S, Krasopoulos G, Sayeed R, Ho LP, Neubauer S, Newby DE, Channon KM, Deanfield J, Antoniades C; COMBAT Consortium; ORFAN investigators. Kotanidis CP, et al. Lancet Digit Health. 2022 Oct;4(10):e705-e716. doi: 10.1016/S2589-7500(22)00132-7. Epub 2022 Aug 26. Lancet Digit Health. 2022. PMID: 36038496 Free PMC article.
A blood atlas of COVID-19 defines hallmarks of disease severity and specificity.
COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk; COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. COvid-19 Multi-omics Blood ATlas (COMBAT) Consortium. Electronic address: julian.knight@well.ox.ac.uk, et al. Cell. 2022 Mar 3;185(5):916-938.e58. doi: 10.1016/j.cell.2022.01.012. Epub 2022 Jan 21. Cell. 2022. PMID: 35216673 Free PMC article.
Cell selectivity in succinate receptor SUCNR1/GPR91 signaling in skeletal muscle.
Abdelmoez AM, Dmytriyeva O, Zurke YX, Trauelsen M, Marica AA, Savikj M, Smith JAB, Monaco C, Schwartz TW, Krook A, Pillon NJ. Abdelmoez AM, et al. Among authors: zurke yx. Am J Physiol Endocrinol Metab. 2023 Apr 1;324(4):E289-E298. doi: 10.1152/ajpendo.00009.2023. Epub 2023 Feb 22. Am J Physiol Endocrinol Metab. 2023. PMID: 36812387 Free article.
Lipoproteins act as vehicles for lipid antigen delivery and activation of invariant natural killer T cells.
Engelen SE, Ververs FA, Markovska A, Lagerholm BC, Kraaijenhof JM, Yousif LI, Zurke YX, Gulersonmez CM, Kooijman S, Goddard M, van Eijkeren RJ, Jervis PJ, Besra GS, Haitjema S, Asselbergs FW, Kalkhoven E, Ploegh HL, Boes M, Cerundolo V, Hovingh GK, Salio M, Stigter EC, Rensen PC, Monaco C, Schipper HS. Engelen SE, et al. Among authors: zurke yx. JCI Insight. 2023 May 8;8(9):e158089. doi: 10.1172/jci.insight.158089. JCI Insight. 2023. PMID: 36976644 Free PMC article.
Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis increasing the risk of cerebrovascular complications.
Dib L, Koneva LA, Edsfeldt A, Zurke YX, Sun J, Nitulescu M, Attar M, Lutgens E, Schmidt S, Lindholm MW, Choudhury RP, Cassimjee I, Lee R, Handa A, Goncalves I, Sansom SN, Monaco C. Dib L, et al. Among authors: zurke yx. Nat Cardiovasc Res. 2023 Jun 26;2(7):656-672. doi: 10.1038/s44161-023-00295-x. Nat Cardiovasc Res. 2023. PMID: 38362263 Free PMC article.
Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.
Weeratunga P, Denney L, Bull JA, Repapi E, Sergeant M, Etherington R, Vuppussetty C, Turner GDH, Clelland C, Woo J, Cross A, Issa F, de Andrea CE, Melero Bermejo I, Sims D, McGowan S, Zurke YX, Ahern DJ, Gamez EC, Whalley J, Richards D, Klenerman P, Monaco C, Udalova IA, Dong T, Antanaviciute A, Ogg G, Knight JC, Byrne HM, Taylor S, Ho LP. Weeratunga P, et al. Among authors: zurke yx. Nat Commun. 2023 Nov 8;14(1):7216. doi: 10.1038/s41467-023-42421-0. Nat Commun. 2023. PMID: 37940670 Free PMC article.
Erratum: Author Correction: Lipid-associated macrophages transition to an inflammatory state in human atherosclerosis, increasing the risk of cerebrovascular complications.
Dib L, Koneva LA, Edsfeldt A, Zurke YX, Sun J, Nitulescu M, Attar M, Lutgens E, Schmidt S, Lindholm MW, Choudhury RP, Cassimjee I, Lee R, Handa A, Goncalves I, Sansom SN, Monaco C. Dib L, et al. Among authors: zurke yx. Nat Cardiovasc Res. 2023;2(9):853. doi: 10.1038/s44161-023-00328-5. Epub 2023 Aug 7. Nat Cardiovasc Res. 2023. PMID: 38665211 Free PMC article.