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Fibrosis induced by resident macrophages has divergent roles in pancreas inflammatory injury and PDAC.
Baer JM, Zuo C, Kang LI, de la Lastra AA, Borcherding NC, Knolhoff BL, Bogner SJ, Zhu Y, Yang L, Laurent J, Lewis MA, Zhang N, Kim KW, Fields RC, Yokoyama WM, Mills JC, Ding L, Randolph GJ, DeNardo DG. Baer JM, et al. Among authors: zuo c. Nat Immunol. 2023 Sep;24(9):1443-1457. doi: 10.1038/s41590-023-01579-x. Epub 2023 Aug 10. Nat Immunol. 2023. PMID: 37563309 Free PMC article.
Stromal and therapy-induced macrophage proliferation promotes PDAC progression and susceptibility to innate immunotherapy.
Zuo C, Baer JM, Knolhoff BL, Belle JI, Liu X, Alarcon De La Lastra A, Fu C, Hogg GD, Kingston NL, Breden MA, Dodhiawala PB, Zhou DC, Lander VE, James CA, Ding L, Lim KH, Fields RC, Hawkins WG, Weber JD, Zhao G, DeNardo DG. Zuo C, et al. J Exp Med. 2023 Jun 5;220(6):e20212062. doi: 10.1084/jem.20212062. Epub 2023 Mar 23. J Exp Med. 2023. PMID: 36951731 Free PMC article.
Stromal Reprogramming by FAK Inhibition Overcomes Radiation Resistance to Allow for Immune Priming and Response to Checkpoint Blockade.
Lander VE, Belle JI, Kingston NL, Herndon JM, Hogg GD, Liu X, Kang LI, Knolhoff BL, Bogner SJ, Baer JM, Zuo C, Borcherding NC, Lander DP, Mpoy C, Scott J, Zahner M, Rogers BE, Schwarz JK, Kim H, DeNardo DG. Lander VE, et al. Among authors: zuo c. Cancer Discov. 2022 Dec 2;12(12):2774-2799. doi: 10.1158/2159-8290.CD-22-0192. Cancer Discov. 2022. PMID: 36165893 Free PMC article.
Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer.
Hegde S, Krisnawan VE, Herzog BH, Zuo C, Breden MA, Knolhoff BL, Hogg GD, Tang JP, Baer JM, Mpoy C, Lee KB, Alexander KA, Rogers BE, Murphy KM, Hawkins WG, Fields RC, DeSelm CJ, Schwarz JK, DeNardo DG. Hegde S, et al. Among authors: zuo c. Cancer Cell. 2020 Mar 16;37(3):289-307.e9. doi: 10.1016/j.ccell.2020.02.008. Cancer Cell. 2020. PMID: 32183949 Free PMC article.
Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-resistant pancreatic cancer.
Cui Zhou D, Jayasinghe RG, Chen S, Herndon JM, Iglesia MD, Navale P, Wendl MC, Caravan W, Sato K, Storrs E, Mo CK, Liu J, Southard-Smith AN, Wu Y, Naser Al Deen N, Baer JM, Fulton RS, Wyczalkowski MA, Liu R, Fronick CC, Fulton LA, Shinkle A, Thammavong L, Zhu H, Sun H, Wang LB, Li Y, Zuo C, McMichael JF, Davies SR, Appelbaum EL, Robbins KJ, Chasnoff SE, Yang X, Reeb AN, Oh C, Serasanambati M, Lal P, Varghese R, Mashl JR, Ponce J, Terekhanova NV, Yao L, Wang F, Chen L, Schnaubelt M, Lu RJ, Schwarz JK, Puram SV, Kim AH, Song SK, Shoghi KI, Lau KS, Ju T, Chen K, Chatterjee D, Hawkins WG, Zhang H, Achilefu S, Chheda MG, Oh ST, Gillanders WE, Chen F, DeNardo DG, Fields RC, Ding L. Cui Zhou D, et al. Among authors: zuo c. Nat Genet. 2022 Sep;54(9):1390-1405. doi: 10.1038/s41588-022-01157-1. Epub 2022 Aug 22. Nat Genet. 2022. PMID: 35995947 Free PMC article.
Context-dependent activation of STING-interferon signaling by CD11b agonists enhances anti-tumor immunity.
Liu X, Hogg GD, Zuo C, Borcherding NC, Baer JM, Lander VE, Kang LI, Knolhoff BL, Ahmad F, Osterhout RE, Galkin AV, Bruey JM, Carter LL, Mpoy C, Vij KR, Fields RC, Schwarz JK, Park H, Gupta V, DeNardo DG. Liu X, et al. Among authors: zuo c. Cancer Cell. 2023 Jun 12;41(6):1073-1090.e12. doi: 10.1016/j.ccell.2023.04.018. Epub 2023 May 25. Cancer Cell. 2023. PMID: 37236195
Neoadjuvant FOLFIRINOX Therapy Is Associated with Increased Effector T Cells and Reduced Suppressor Cells in Patients with Pancreatic Cancer.
Peng H, James CA, Cullinan DR, Hogg GD, Mudd JL, Zuo C, Takchi R, Caldwell KE, Liu J, DeNardo DG, Fields RC, Gillanders WE, Goedegebuure SP, Hawkins WG. Peng H, et al. Among authors: zuo c. Clin Cancer Res. 2021 Dec 15;27(24):6761-6771. doi: 10.1158/1078-0432.CCR-21-0998. Epub 2021 Sep 30. Clin Cancer Res. 2021. PMID: 34593529 Free PMC article.
1,413 results