Zunke F - Search Results

1

α-Synuclein in Parkinson's disease: causal or bystander?

Riederer P, Berg D, Casadei N, Cheng F, Classen J, Dresel C, Jost W, Krüger R, Müller T, Reichmann H, Rieß O, Storch A, Strobel S, van Eimeren T, Völker HU, Winkler J, Winklhofer KF, Wüllner U, Zunke F, Monoranu CM. Riederer P, et al. Among authors: zunke f. J Neural Transm (Vienna). 2019 Jul;126(7):815-840. doi: 10.1007/s00702-019-02025-9. Epub 2019 Jun 25. J Neural Transm (Vienna). 2019. PMID: 31240402 Review.

2

Alpha Synuclein Connects the Gut-Brain Axis in Parkinson's Disease Patients - A View on Clinical Aspects, Cellular Pathology and Analytical Methodology.

Schaeffer E, Kluge A, Böttner M, Zunke F, Cossais F, Berg D, Arnold P. Schaeffer E, et al. Among authors: zunke f. Front Cell Dev Biol. 2020 Sep 8;8:573696. doi: 10.3389/fcell.2020.573696. eCollection 2020. Front Cell Dev Biol. 2020. PMID: 33015066 Free PMC article. Review.

3

Rescue of α-synuclein aggregation in Parkinson's patient neurons by synergistic enhancement of ER proteostasis and protein trafficking.

Stojkovska I, Wani WY, Zunke F, Belur NR, Pavlenko EA, Mwenda N, Sharma K, Francelle L, Mazzulli JR. Stojkovska I, et al. Among authors: zunke f. Neuron. 2022 Feb 2;110(3):436-451.e11. doi: 10.1016/j.neuron.2021.10.032. Epub 2021 Nov 17. Neuron. 2022. PMID: 34793693 Free PMC article.

4

Interaction of Alpha Synuclein and Microtubule Organization Is Linked to Impaired Neuritic Integrity in Parkinson's Patient-Derived Neuronal Cells.

Seebauer L, Schneider Y, Drobny A, Plötz S, Koudelka T, Tholey A, Prots I, Winner B, Zunke F, Winkler J, Xiang W. Seebauer L, et al. Among authors: zunke f. Int J Mol Sci. 2022 Feb 5;23(3):1812. doi: 10.3390/ijms23031812. Int J Mol Sci. 2022. PMID: 35163733 Free PMC article.

5

Detection of neuron-derived pathological α-synuclein in blood.

Kluge A, Bunk J, Schaeffer E, Drobny A, Xiang W, Knacke H, Bub S, Lückstädt W, Arnold P, Lucius R, Berg D, Zunke F. Kluge A, et al. Among authors: zunke f. Brain. 2022 Sep 14;145(9):3058-3071. doi: 10.1093/brain/awac115. Brain. 2022. PMID: 35722765

6

Reciprocal effects of alpha-synuclein aggregation and lysosomal homeostasis in synucleinopathy models.

Drobny A, Boros FA, Balta D, Prieto Huarcaya S, Caylioglu D, Qazi N, Vandrey J, Schneider Y, Dobert JP, Pitcairn C, Mazzulli JR, Zunke F. Drobny A, et al. Among authors: zunke f. Transl Neurodegener. 2023 Jun 13;12(1):31. doi: 10.1186/s40035-023-00363-z. Transl Neurodegener. 2023. PMID: 37312133 Free PMC article.

7

Gut-to-brain spreading of pathology in synucleinopathies: A focus on molecular signalling mediators.

Schmitt V, Masanetz RK, Weidenfeller M, Ebbinghaus LS, Süß P, Rosshart SP, von Hörsten S, Zunke F, Winkler J, Xiang W. Schmitt V, et al. Among authors: zunke f. Behav Brain Res. 2023 Aug 24;452:114574. doi: 10.1016/j.bbr.2023.114574. Epub 2023 Jul 8. Behav Brain Res. 2023. PMID: 37423320 Free article. Review.

8

LIMP-2 expression is critical for β-glucocerebrosidase activity and α-synuclein clearance.

Rothaug M, Zunke F, Mazzulli JR, Schweizer M, Altmeppen H, Lüllmann-Rauch R, Kallemeijn WW, Gaspar P, Aerts JM, Glatzel M, Saftig P, Krainc D, Schwake M, Blanz J. Rothaug M, et al. Among authors: zunke f. Proc Natl Acad Sci U S A. 2014 Oct 28;111(43):15573-8. doi: 10.1073/pnas.1405700111. Epub 2014 Oct 14. Proc Natl Acad Sci U S A. 2014. PMID: 25316793 Free PMC article.

9

α-Synuclein-induced lysosomal dysfunction occurs through disruptions in protein trafficking in human midbrain synucleinopathy models.

Mazzulli JR, Zunke F, Isacson O, Studer L, Krainc D. Mazzulli JR, et al. Among authors: zunke f. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1931-6. doi: 10.1073/pnas.1520335113. Epub 2016 Feb 2. Proc Natl Acad Sci U S A. 2016. PMID: 26839413 Free PMC article.

10

Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.

Mazzulli JR, Zunke F, Tsunemi T, Toker NJ, Jeon S, Burbulla LF, Patnaik S, Sidransky E, Marugan JJ, Sue CM, Krainc D. Mazzulli JR, et al. Among authors: zunke f. J Neurosci. 2016 Jul 20;36(29):7693-706. doi: 10.1523/JNEUROSCI.0628-16.2016. J Neurosci. 2016. PMID: 27445146 Free PMC article.

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