Zu T - Search Results

1

SCA8 RAN polySer protein preferentially accumulates in white matter regions and is regulated by eIF3F.

Ayhan F, Perez BA, Shorrock HK, Zu T, Banez-Coronel M, Reid T, Furuya H, Clark HB, Troncoso JC, Ross CA, Subramony SH, Ashizawa T, Wang ET, Yachnis AT, Ranum LP. Ayhan F, et al. Among authors: zu t. EMBO J. 2018 Oct 1;37(19):e99023. doi: 10.15252/embj.201899023. Epub 2018 Sep 11. EMBO J. 2018. PMID: 30206144 Free PMC article.

2

RAN Translation in Huntington Disease.

Bañez-Coronel M, Ayhan F, Tarabochia AD, Zu T, Perez BA, Tusi SK, Pletnikova O, Borchelt DR, Ross CA, Margolis RL, Yachnis AT, Troncoso JC, Ranum LP. Bañez-Coronel M, et al. Among authors: zu t. Neuron. 2015 Nov 18;88(4):667-77. doi: 10.1016/j.neuron.2015.10.038. Neuron. 2015. PMID: 26590344 Free PMC article.

3

RAN Translation Regulated by Muscleblind Proteins in Myotonic Dystrophy Type 2.

Zu T, Cleary JD, Liu Y, Bañez-Coronel M, Bubenik JL, Ayhan F, Ashizawa T, Xia G, Clark HB, Yachnis AT, Swanson MS, Ranum LPW. Zu T, et al. Neuron. 2017 Sep 13;95(6):1292-1305.e5. doi: 10.1016/j.neuron.2017.08.039. Neuron. 2017. PMID: 28910618 Free PMC article.

4

CCG•CGG interruptions in high-penetrance SCA8 families increase RAN translation and protein toxicity.

Perez BA, Shorrock HK, Banez-Coronel M, Zu T, Romano LE, Laboissonniere LA, Reid T, Ikeda Y, Reddy K, Gomez CM, Bird T, Ashizawa T, Schut LJ, Brusco A, Berglund JA, Hasholt LF, Nielsen JE, Subramony SH, Ranum LP. Perez BA, et al. Among authors: zu t. EMBO Mol Med. 2021 Nov 8;13(11):e14095. doi: 10.15252/emmm.202114095. Epub 2021 Oct 11. EMBO Mol Med. 2021. PMID: 34632710 Free PMC article.

5

Bidirectional expression of CUG and CAG expansion transcripts and intranuclear polyglutamine inclusions in spinocerebellar ataxia type 8.

Moseley ML, Zu T, Ikeda Y, Gao W, Mosemiller AK, Daughters RS, Chen G, Weatherspoon MR, Clark HB, Ebner TJ, Day JW, Ranum LP. Moseley ML, et al. Among authors: zu t. Nat Genet. 2006 Jul;38(7):758-69. doi: 10.1038/ng1827. Epub 2006 Jun 25. Nat Genet. 2006. PMID: 16804541

6

RAN proteins and RNA foci from antisense transcripts in C9ORF72 ALS and frontotemporal dementia.

Zu T, Liu Y, Bañez-Coronel M, Reid T, Pletnikova O, Lewis J, Miller TM, Harms MB, Falchook AE, Subramony SH, Ostrow LW, Rothstein JD, Troncoso JC, Ranum LP. Zu T, et al. Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):E4968-77. doi: 10.1073/pnas.1315438110. Epub 2013 Nov 18. Proc Natl Acad Sci U S A. 2013. PMID: 24248382 Free PMC article. Clinical Trial.

7

C9orf72 BAC Mouse Model with Motor Deficits and Neurodegenerative Features of ALS/FTD.

Liu Y, Pattamatta A, Zu T, Reid T, Bardhi O, Borchelt DR, Yachnis AT, Ranum LP. Liu Y, et al. Among authors: zu t. Neuron. 2016 May 4;90(3):521-34. doi: 10.1016/j.neuron.2016.04.005. Epub 2016 Apr 21. Neuron. 2016. PMID: 27112499 Free article.

8

Repeat-Associated Non-ATG Translation in Neurological Diseases.

Zu T, Pattamatta A, Ranum LPW. Zu T, et al. Cold Spring Harb Perspect Biol. 2018 Dec 3;10(12):a033019. doi: 10.1101/cshperspect.a033019. Cold Spring Harb Perspect Biol. 2018. PMID: 29891563 Free PMC article. Review.

9

The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG•CAGG repeats.

Tusi SK, Nguyen L, Thangaraju K, Li J, Cleary JD, Zu T, Ranum LPW. Tusi SK, et al. Among authors: zu t. Hum Mol Genet. 2021 May 31;30(11):1020-1029. doi: 10.1093/hmg/ddab098. Hum Mol Genet. 2021. PMID: 33856033 Free PMC article.

10

Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits.

He Y, Zu T, Benzow KA, Orr HT, Clark HB, Koob MD. He Y, et al. Among authors: zu t. J Neurosci. 2006 Sep 27;26(39):9975-82. doi: 10.1523/JNEUROSCI.2595-06.2006. J Neurosci. 2006. PMID: 17005861 Free PMC article.

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