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Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis.
Gómez-Valadés AG, Pozo M, Varela L, Boudjadja MB, Ramírez S, Chivite I, Eyre E, Haddad-Tóvolli R, Obri A, Milà-Guasch M, Altirriba J, Schneeberger M, Imbernón M, Garcia-Rendueles AR, Gama-Perez P, Rojo-Ruiz J, Rácz B, Alonso MT, Gomis R, Zorzano A, D'Agostino G, Alvarez CV, Nogueiras R, Garcia-Roves PM, Horvath TL, Claret M. Gómez-Valadés AG, et al. Among authors: zorzano a. Cell Metab. 2021 Sep 7;33(9):1820-1835.e9. doi: 10.1016/j.cmet.2021.07.008. Epub 2021 Aug 2. Cell Metab. 2021. PMID: 34343501 Free PMC article.
Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis.
Sebastián D, Hernández-Alvarez MI, Segalés J, Sorianello E, Muñoz JP, Sala D, Waget A, Liesa M, Paz JC, Gopalacharyulu P, Orešič M, Pich S, Burcelin R, Palacín M, Zorzano A. Sebastián D, et al. Among authors: zorzano a. Proc Natl Acad Sci U S A. 2012 Apr 3;109(14):5523-8. doi: 10.1073/pnas.1108220109. Epub 2012 Mar 16. Proc Natl Acad Sci U S A. 2012. PMID: 22427360 Free PMC article.
Mitofusin 2 in POMC neurons connects ER stress with leptin resistance and energy imbalance.
Schneeberger M, Dietrich MO, Sebastián D, Imbernón M, Castaño C, Garcia A, Esteban Y, Gonzalez-Franquesa A, Rodríguez IC, Bortolozzi A, Garcia-Roves PM, Gomis R, Nogueiras R, Horvath TL, Zorzano A, Claret M. Schneeberger M, et al. Among authors: zorzano a. Cell. 2013 Sep 26;155(1):172-87. doi: 10.1016/j.cell.2013.09.003. Cell. 2013. PMID: 24074867 Free PMC article.
p38α function in osteoblasts influences adipose tissue homeostasis.
Rodríguez-Carballo E, Gámez B, Méndez-Lucas A, Sánchez-Freutrie M, Zorzano A, Bartrons R, Alcántara S, Perales JC, Ventura F. Rodríguez-Carballo E, et al. Among authors: zorzano a. FASEB J. 2015 Apr;29(4):1414-25. doi: 10.1096/fj.14-261891. Epub 2014 Dec 30. FASEB J. 2015. PMID: 25550462
Reduced α-MSH Underlies Hypothalamic ER-Stress-Induced Hepatic Gluconeogenesis.
Schneeberger M, Gómez-Valadés AG, Altirriba J, Sebastián D, Ramírez S, Garcia A, Esteban Y, Drougard A, Ferrés-Coy A, Bortolozzi A, Garcia-Roves PM, Jones JG, Manadas B, Zorzano A, Gomis R, Claret M. Schneeberger M, et al. Among authors: zorzano a. Cell Rep. 2015 Jul 21;12(3):361-70. doi: 10.1016/j.celrep.2015.06.041. Epub 2015 Jul 9. Cell Rep. 2015. PMID: 26166568 Free article.
Mfn2 is critical for brown adipose tissue thermogenic function.
Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C. Boutant M, et al. Among authors: zorzano a. EMBO J. 2017 Jun 1;36(11):1543-1558. doi: 10.15252/embj.201694914. Epub 2017 Mar 27. EMBO J. 2017. PMID: 28348166 Free PMC article.
Mitochondrial Dynamics Mediated by Mitofusin 1 Is Required for POMC Neuron Glucose-Sensing and Insulin Release Control.
Ramírez S, Gómez-Valadés AG, Schneeberger M, Varela L, Haddad-Tóvolli R, Altirriba J, Noguera E, Drougard A, Flores-Martínez Á, Imbernón M, Chivite I, Pozo M, Vidal-Itriago A, Garcia A, Cervantes S, Gasa R, Nogueiras R, Gama-Pérez P, Garcia-Roves PM, Cano DA, Knauf C, Servitja JM, Horvath TL, Gomis R, Zorzano A, Claret M. Ramírez S, et al. Among authors: zorzano a. Cell Metab. 2017 Jun 6;25(6):1390-1399.e6. doi: 10.1016/j.cmet.2017.05.010. Cell Metab. 2017. PMID: 28591639 Free article.
Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency.
Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A. Rodríguez-Nuevo A, et al. Among authors: zorzano a. EMBO J. 2018 May 15;37(10):e96553. doi: 10.15252/embj.201796553. Epub 2018 Apr 9. EMBO J. 2018. PMID: 29632021 Free PMC article.
372 results