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A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice.
Kuang Y, Zorzi V, Buratto D, Ziraldo G, Mazzarda F, Peres C, Nardin C, Salvatore AM, Chiani F, Scavizzi F, Raspa M, Qiang M, Chu Y, Shi X, Li Y, Liu L, Shi Y, Zonta F, Yang G, Lerner RA, Mammano F. Kuang Y, et al. Among authors: zonta f. EBioMedicine. 2020 Jul;57:102825. doi: 10.1016/j.ebiom.2020.102825. Epub 2020 Jun 15. EBioMedicine. 2020. PMID: 32553574 Free PMC article.
A fully atomistic model of the Cx32 connexon.
Pantano S, Zonta F, Mammano F. Pantano S, et al. Among authors: zonta f. PLoS One. 2008 Jul 2;3(7):e2614. doi: 10.1371/journal.pone.0002614. PLoS One. 2008. PMID: 18648547 Free PMC article.
The p.Cys169Tyr variant of connexin 26 is not a polymorphism.
Zonta F, Girotto G, Buratto D, Crispino G, Morgan A, Abdulhadi K, Alkowari M, Badii R, Gasparini P, Mammano F. Zonta F, et al. Hum Mol Genet. 2015 May 1;24(9):2641-8. doi: 10.1093/hmg/ddv026. Epub 2015 Jan 26. Hum Mol Genet. 2015. PMID: 25628337 Free PMC article.
Design and Characterization of a Human Monoclonal Antibody that Modulates Mutant Connexin 26 Hemichannels Implicated in Deafness and Skin Disorders.
Xu L, Carrer A, Zonta F, Qu Z, Ma P, Li S, Ceriani F, Buratto D, Crispino G, Zorzi V, Ziraldo G, Bruno F, Nardin C, Peres C, Mazzarda F, Salvatore AM, Raspa M, Scavizzi F, Chu Y, Xie S, Yang X, Liao J, Liu X, Wang W, Wang S, Yang G, Lerner RA, Mammano F. Xu L, et al. Among authors: zonta f. Front Mol Neurosci. 2017 Sep 22;10:298. doi: 10.3389/fnmol.2017.00298. eCollection 2017. Front Mol Neurosci. 2017. PMID: 29018324 Free PMC article.
145 results