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Distinct in vitro binding properties of the anti-CD20 small modular immunopharmaceutical 2LM20-4 result in profound and sustained in vivo potency in cynomolgus monkeys.
Nickerson-Nutter C, Tchistiakova L, Seth NP, Kasaian M, Sibley B, Olland S, Zollner R, Brady WA, Mohler KM, Baum P, Wahl A, Herber D, Vugmeyster Y, Wensel D, Wolfman NM, Gill D, Collins M, Dunussi-Joannopoulos K. Nickerson-Nutter C, et al. Among authors: zollner r. Rheumatology (Oxford). 2011 Jun;50(6):1033-44. doi: 10.1093/rheumatology/keq423. Epub 2011 Jan 21. Rheumatology (Oxford). 2011. PMID: 21258049 Free PMC article.
Oligomerization is required for the activity of recombinant soluble LOX-1.
Cao W, Calabro V, Root A, Yan G, Lam K, Olland S, Sanford J, Robak A, Zollner R, Lu Z, Ait-Zahra M, Agostinelli R, Tchistiakova L, Gill D, Harnish D, Paulsen J, Shih HH. Cao W, et al. Among authors: zollner r. FEBS J. 2009 Sep;276(17):4909-20. doi: 10.1111/j.1742-4658.2009.07190.x. Epub 2009 Jul 31. FEBS J. 2009. PMID: 19664054 Free article.
Temporal associations between interleukin 22 and the extracellular domains of IL-22R and IL-10R2.
Li J, Tomkinson KN, Tan XY, Wu P, Yan G, Spaulding V, Deng B, Annis-Freeman B, Heveron K, Zollner R, De Zutter G, Wright JF, Crawford TK, Liu W, Jacobs KA, Wolfman NM, Ling V, Pittman DD, Veldman GM, Fouser LA. Li J, et al. Among authors: zollner r. Int Immunopharmacol. 2004 May;4(5):693-708. doi: 10.1016/j.intimp.2004.01.010. Int Immunopharmacol. 2004. PMID: 15120653 Review.
Mechanistic understanding of the cysteine capping modifications of antibodies enables selective chemical engineering in live mammalian cells.
Zhong X, He T, Prashad AS, Wang W, Cohen J, Ferguson D, Tam AS, Sousa E, Lin L, Tchistiakova L, Gatto S, D'Antona A, Luan YT, Ma W, Zollner R, Zhou J, Arve B, Somers W, Kriz R. Zhong X, et al. Among authors: zollner r. J Biotechnol. 2017 Apr 20;248:48-58. doi: 10.1016/j.jbiotec.2017.03.006. Epub 2017 Mar 11. J Biotechnol. 2017. PMID: 28300660
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Mosyak L, Georgiadis K, Shane T, Svenson K, Hebert T, McDonagh T, Mackie S, Olland S, Lin L, Zhong X, Kriz R, Reifenberg EL, Collins-Racie LA, Corcoran C, Freeman B, Zollner R, Marvell T, Vera M, Sum PE, Lavallie ER, Stahl M, Somers W. Mosyak L, et al. Among authors: zollner r. Protein Sci. 2008 Jan;17(1):16-21. doi: 10.1110/ps.073287008. Epub 2007 Nov 27. Protein Sci. 2008. PMID: 18042673 Free PMC article.
Optimization of experimental conditions for functional in vitro characterization of humanized antibodies specific for staphylococcal enterotoxin B.
MacIntyre JL, Varshney AK, Wang X, Gatto S, Friedman C, Liu Y, Kerns K, Kovalenko O, Adkins K, Zollner R, Fries BC, Byrne FR. MacIntyre JL, et al. Among authors: zollner r. Int Immunopharmacol. 2015 Sep;28(1):354-8. doi: 10.1016/j.intimp.2015.06.025. Epub 2015 Jun 27. Int Immunopharmacol. 2015. PMID: 26130567 Free PMC article.
Transient CHO expression platform for robust antibody production and its enhanced N-glycan sialylation on therapeutic glycoproteins.
Zhong X, Ma W, Meade CL, Tam AS, Llewellyn E, Cornell R, Cote K, Scarcelli JJ, Marshall JK, Tzvetkova B, Figueroa B, DiNino D, Sievers A, Lee C, Guo J, Mahan E, Francis C, Lam K, D'Antona AM, Zollner R, Zhu HL, Kriz R, Somers W, Lin L. Zhong X, et al. Among authors: zollner r. Biotechnol Prog. 2019 Jan;35(1):e2724. doi: 10.1002/btpr.2724. Epub 2018 Oct 27. Biotechnol Prog. 2019. PMID: 30299005
93 results