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Pharmacological disruption of the Notch transcription factor complex.
Lehal R, Zaric J, Vigolo M, Urech C, Frismantas V, Zangger N, Cao L, Berger A, Chicote I, Loubéry S, Choi SH, Koch U, Blacklow SC, Palmer HG, Bornhauser B, González-Gaitán M, Arsenijevic Y, Zoete V, Aster JC, Bourquin JP, Radtke F. Lehal R, et al. Among authors: zoete v. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16292-16301. doi: 10.1073/pnas.1922606117. Epub 2020 Jun 29. Proc Natl Acad Sci U S A. 2020. PMID: 32601208 Free PMC article.
Rational design of indoleamine 2,3-dioxygenase inhibitors.
Röhrig UF, Awad L, Grosdidier A, Larrieu P, Stroobant V, Colau D, Cerundolo V, Simpson AJ, Vogel P, Van den Eynde BJ, Zoete V, Michielin O. Röhrig UF, et al. Among authors: zoete v. J Med Chem. 2010 Feb 11;53(3):1172-89. doi: 10.1021/jm9014718. J Med Chem. 2010. PMID: 20055453
Pan-SRC kinase inhibition blocks B-cell receptor oncogenic signaling in non-Hodgkin lymphoma.
Battistello E, Katanayeva N, Dheilly E, Tavernari D, Donaldson MC, Bonsignore L, Thome M, Christie AL, Murakami MA, Michielin O, Ciriello G, Zoete V, Oricchio E. Battistello E, et al. Among authors: zoete v. Blood. 2018 May 24;131(21):2345-2356. doi: 10.1182/blood-2017-10-809210. Epub 2018 Mar 22. Blood. 2018. PMID: 29567799 Free PMC article.
Influenza A viruses balance ER stress with host protein synthesis shutoff.
Mazel-Sanchez B, Iwaszkiewicz J, Bonifacio JPP, Silva F, Niu C, Strohmeier S, Eletto D, Krammer F, Tan G, Zoete V, Hale BG, Schmolke M. Mazel-Sanchez B, et al. Among authors: zoete v. Proc Natl Acad Sci U S A. 2021 Sep 7;118(36):e2024681118. doi: 10.1073/pnas.2024681118. Proc Natl Acad Sci U S A. 2021. PMID: 34479996 Free PMC article.
Distinct sets of alphabeta TCRs confer similar recognition of tumor antigen NY-ESO-1157-165 by interacting with its central Met/Trp residues.
Derré L, Bruyninx M, Baumgaertner P, Ferber M, Schmid D, Leimgruber A, Zoete V, Romero P, Michielin O, Speiser DE, Rufer N. Derré L, et al. Among authors: zoete v. Proc Natl Acad Sci U S A. 2008 Sep 30;105(39):15010-5. doi: 10.1073/pnas.0807954105. Epub 2008 Sep 22. Proc Natl Acad Sci U S A. 2008. PMID: 18809922 Free PMC article.
Shaping the interaction landscape of bioactive molecules.
Gfeller D, Michielin O, Zoete V. Gfeller D, et al. Among authors: zoete v. Bioinformatics. 2013 Dec 1;29(23):3073-9. doi: 10.1093/bioinformatics/btt540. Epub 2013 Sep 17. Bioinformatics. 2013. PMID: 24048355
Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases.
Murone M, Vaslin Chessex A, Attinger A, Ramachandra R, Shetty SJ, Daginakatte G, Sengupta S, Marappan S, Dhodheri S, Rigotti S, Bachhav Y, Brienza S, Traxler P, Lang M, Aguet M, Zoete V, Michielin O, Nicholas C, Johnson FM, Ramachandra M, McAllister A. Murone M, et al. Among authors: zoete v. Mol Cancer Ther. 2016 Oct;15(10):2334-2343. doi: 10.1158/1535-7163.MCT-15-0974. Epub 2016 Jul 20. Mol Cancer Ther. 2016. PMID: 27439479
165 results