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Synoviocyte-targeted therapy synergizes with TNF inhibition in arthritis reversal.
Svensson MND, Zoccheddu M, Yang S, Nygaard G, Secchi C, Doody KM, Slowikowski K, Mizoguchi F, Humby F, Hands R, Santelli E, Sacchetti C, Wakabayashi K, Wu DJ, Barback C, Ai R, Wang W, Sims GP, Mydel P, Kasama T, Boyle DL, Galimi F, Vera D, Tremblay ML, Raychaudhuri S, Brenner MB, Firestein GS, Pitzalis C, Ekwall AH, Stanford SM, Bottini N. Svensson MND, et al. Among authors: zoccheddu m. Sci Adv. 2020 Jun 26;6(26):eaba4353. doi: 10.1126/sciadv.aba4353. eCollection 2020 Jun. Sci Adv. 2020. PMID: 32637608 Free PMC article.
PTPN14 phosphatase and YAP promote TGFβ signalling in rheumatoid synoviocytes.
Bottini A, Wu DJ, Ai R, Le Roux M, Bartok B, Bombardieri M, Doody KM, Zhang V, Sacchetti C, Zoccheddu M, Lonic A, Li X, Boyle DL, Hammaker D, Meng TC, Liu L, Corr M, Stanford SM, Lewis M, Wang W, Firestein GS, Khew-Goodall Y, Pitzalis C, Bottini N. Bottini A, et al. Among authors: zoccheddu m. Ann Rheum Dis. 2019 May;78(5):600-609. doi: 10.1136/annrheumdis-2018-213799. Epub 2019 Feb 26. Ann Rheum Dis. 2019. PMID: 30808624 Free PMC article.
Immunomodulatory Nanoparticles for Modulating Arthritis Flares.
Johnson WT, McBride D, Kerr M, Nguyen A, Zoccheddu M, Bollmann M, Wei X, Jones RM, Wang W, Svensson MND, Bottini N, Shah NJ. Johnson WT, et al. Among authors: zoccheddu m. ACS Nano. 2024 Jan 23;18(3):1892-1906. doi: 10.1021/acsnano.3c05298. Epub 2023 Nov 28. ACS Nano. 2024. PMID: 38016062
Graphene oxide activates B cells with upregulation of granzyme B expression: evidence at the single-cell level for its immune-modulatory properties and anticancer activity.
Orecchioni M, Fusco L, Mall R, Bordoni V, Fuoco C, Rinchai D, Guo S, Sainz R, Zoccheddu M, Gurcan C, Yilmazer A, Zavan B, Ménard-Moyon C, Bianco A, Hendrickx W, Bedognetti D, Delogu LG. Orecchioni M, et al. Among authors: zoccheddu m. Nanoscale. 2022 Jan 6;14(2):333-349. doi: 10.1039/d1nr04355b. Nanoscale. 2022. PMID: 34796889