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The liver and muscle secreted HFE2-protein maintains central nervous system blood vessel integrity.
Wang XF, Vigouroux R, Syonov M, Baglaenko Y, Nikolakopoulou AM, Ringuette D, Rus H, DiStefano PV, Dufour S, Shabanzadeh AP, Lee S, Mueller BK, Charish J, Harada H, Fish JE, Wither J, Wälchli T, Cloutier JF, Zlokovic BV, Carlen PL, Monnier PP. Wang XF, et al. Among authors: zlokovic bv. Nat Commun. 2024 Feb 3;15(1):1037. doi: 10.1038/s41467-024-45303-1. Nat Commun. 2024. PMID: 38310100 Free PMC article.
Central nervous system pericytes in health and disease.
Winkler EA, Bell RD, Zlokovic BV. Winkler EA, et al. Among authors: zlokovic bv. Nat Neurosci. 2011 Oct 26;14(11):1398-1405. doi: 10.1038/nn.2946. Nat Neurosci. 2011. PMID: 22030551 Free PMC article.
Pericyte loss influences Alzheimer-like neurodegeneration in mice.
Sagare AP, Bell RD, Zhao Z, Ma Q, Winkler EA, Ramanathan A, Zlokovic BV. Sagare AP, et al. Among authors: zlokovic bv. Nat Commun. 2013;4:2932. doi: 10.1038/ncomms3932. Nat Commun. 2013. PMID: 24336108 Free PMC article. Retracted.
Pericyte degeneration causes white matter dysfunction in the mouse central nervous system.
Montagne A, Nikolakopoulou AM, Zhao Z, Sagare AP, Si G, Lazic D, Barnes SR, Daianu M, Ramanathan A, Go A, Lawson EJ, Wang Y, Mack WJ, Thompson PM, Schneider JA, Varkey J, Langen R, Mullins E, Jacobs RE, Zlokovic BV. Montagne A, et al. Among authors: zlokovic bv. Nat Med. 2018 Mar;24(3):326-337. doi: 10.1038/nm.4482. Epub 2018 Feb 5. Nat Med. 2018. PMID: 29400711 Free PMC article. Retracted.
Blood-Brain Barrier: From Physiology to Disease and Back.
Sweeney MD, Zhao Z, Montagne A, Nelson AR, Zlokovic BV. Sweeney MD, et al. Among authors: zlokovic bv. Physiol Rev. 2019 Jan 1;99(1):21-78. doi: 10.1152/physrev.00050.2017. Physiol Rev. 2019. PMID: 30280653 Free PMC article. Review.
Pericyte loss leads to circulatory failure and pleiotrophin depletion causing neuron loss.
Nikolakopoulou AM, Montagne A, Kisler K, Dai Z, Wang Y, Huuskonen MT, Sagare AP, Lazic D, Sweeney MD, Kong P, Wang M, Owens NC, Lawson EJ, Xie X, Zhao Z, Zlokovic BV. Nikolakopoulou AM, et al. Among authors: zlokovic bv. Nat Neurosci. 2019 Jul;22(7):1089-1098. doi: 10.1038/s41593-019-0434-z. Epub 2019 Jun 24. Nat Neurosci. 2019. PMID: 31235908 Free PMC article.
315 results