Zjawiony JK - Search Results

1

Novel activities of CYP11A1 and their potential physiological significance.

Slominski AT, Li W, Kim TK, Semak I, Wang J, Zjawiony JK, Tuckey RC. Slominski AT, et al. Among authors: zjawiony jk. J Steroid Biochem Mol Biol. 2015 Jul;151:25-37. doi: 10.1016/j.jsbmb.2014.11.010. Epub 2014 Nov 13. J Steroid Biochem Mol Biol. 2015. PMID: 25448732 Free PMC article. Review.

2

Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc.

Tuckey RC, Li W, Zjawiony JK, Zmijewski MA, Nguyen MN, Sweatman T, Miller D, Slominski A. Tuckey RC, et al. Among authors: zjawiony jk. FEBS J. 2008 May;275(10):2585-96. doi: 10.1111/j.1742-4658.2008.06406.x. Epub 2008 Apr 10. FEBS J. 2008. PMID: 18410379 Free PMC article.

3

Human cytochrome P450scc (CYP11A1) catalyzes epoxide formation with ergosterol.

Tuckey RC, Nguyen MN, Chen J, Slominski AT, Baldisseri DM, Tieu EW, Zjawiony JK, Li W. Tuckey RC, et al. Among authors: zjawiony jk. Drug Metab Dispos. 2012 Mar;40(3):436-44. doi: 10.1124/dmd.111.042515. Epub 2011 Nov 21. Drug Metab Dispos. 2012. PMID: 22106170 Free PMC article.

4

The cytochrome P450scc system opens an alternate pathway of vitamin D3 metabolism.

Slominski A, Semak I, Zjawiony J, Wortsman J, Li W, Szczesniewski A, Tuckey RC. Slominski A, et al. FEBS J. 2005 Aug;272(16):4080-90. doi: 10.1111/j.1742-4658.2005.04819.x. FEBS J. 2005. PMID: 16098191 Free PMC article.

5

Enzymatic metabolism of ergosterol by cytochrome p450scc to biologically active 17alpha,24-dihydroxyergosterol.

Slominski A, Semak I, Zjawiony J, Wortsman J, Gandy MN, Li J, Zbytek B, Li W, Tuckey RC. Slominski A, et al. Chem Biol. 2005 Aug;12(8):931-9. doi: 10.1016/j.chembiol.2005.06.010. Chem Biol. 2005. PMID: 16125105

6

An alternative pathway of vitamin D metabolism. Cytochrome P450scc (CYP11A1)-mediated conversion to 20-hydroxyvitamin D2 and 17,20-dihydroxyvitamin D2.

Slominski A, Semak I, Wortsman J, Zjawiony J, Li W, Zbytek B, Tuckey RC. Slominski A, et al. FEBS J. 2006 Jul;273(13):2891-901. doi: 10.1111/j.1742-4658.2006.05302.x. FEBS J. 2006. PMID: 16817851 Free PMC article.

7

Metabolism of 1alpha-hydroxyvitamin D3 by cytochrome P450scc to biologically active 1alpha,20-dihydroxyvitamin D3.

Tuckey RC, Janjetovic Z, Li W, Nguyen MN, Zmijewski MA, Zjawiony J, Slominski A. Tuckey RC, et al. J Steroid Biochem Mol Biol. 2008 Dec;112(4-5):213-9. doi: 10.1016/j.jsbmb.2008.10.005. Epub 2008 Oct 21. J Steroid Biochem Mol Biol. 2008. PMID: 19000766 Free PMC article.

8

Products of vitamin D3 or 7-dehydrocholesterol metabolism by cytochrome P450scc show anti-leukemia effects, having low or absent calcemic activity.

Slominski AT, Janjetovic Z, Fuller BE, Zmijewski MA, Tuckey RC, Nguyen MN, Sweatman T, Li W, Zjawiony J, Miller D, Chen TC, Lozanski G, Holick MF. Slominski AT, et al. PLoS One. 2010 Mar 26;5(3):e9907. doi: 10.1371/journal.pone.0009907. PLoS One. 2010. PMID: 20360850 Free PMC article.

9

Chemical synthesis of 20S-hydroxyvitamin D3, which shows antiproliferative activity.

Li W, Chen J, Janjetovic Z, Kim TK, Sweatman T, Lu Y, Zjawiony J, Tuckey RC, Miller D, Slominski A. Li W, et al. Steroids. 2010 Dec;75(12):926-35. doi: 10.1016/j.steroids.2010.05.021. Epub 2010 Jun 11. Steroids. 2010. PMID: 20542050 Free PMC article.

10

Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3beta, 17alpha, 20-triol and their bioactivity in melanoma cells.

Zmijewski MA, Li W, Zjawiony JK, Sweatman TW, Chen J, Miller DD, Slominski AT. Zmijewski MA, et al. Among authors: zjawiony jk. Steroids. 2009 Feb;74(2):218-28. doi: 10.1016/j.steroids.2008.10.017. Epub 2008 Nov 6. Steroids. 2009. PMID: 19028513 Free PMC article.

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