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Identification of Effective Anticancer G-Quadruplex-Targeting Chemotypes through the Exploration of a High Diversity Library of Natural Compounds.
Platella C, Ghirga F, Zizza P, Pompili L, Marzano S, Pagano B, Quaglio D, Vergine V, Cammarone S, Botta B, Biroccio A, Mori M, Montesarchio D. Platella C, et al. Among authors: zizza p. Pharmaceutics. 2021 Oct 3;13(10):1611. doi: 10.3390/pharmaceutics13101611. Pharmaceutics. 2021. PMID: 34683905 Free PMC article.
Evidence for G-quadruplex in the promoter of vegfr-2 and its targeting to inhibit tumor angiogenesis.
Salvati E, Zizza P, Rizzo A, Iachettini S, Cingolani C, D'Angelo C, Porru M, Randazzo A, Pagano B, Novellino E, Pisanu ME, Stoppacciaro A, Spinella F, Bagnato A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: zizza p. Nucleic Acids Res. 2014 Mar;42(5):2945-57. doi: 10.1093/nar/gkt1289. Epub 2013 Dec 11. Nucleic Acids Res. 2014. PMID: 24335081 Free PMC article.
Shading the TRF2 recruiting function: a new horizon in drug development.
Di Maro S, Zizza P, Salvati E, De Luca V, Capasso C, Fotticchia I, Pagano B, Marinelli L, Gilson E, Novellino E, Cosconati S, Biroccio A. Di Maro S, et al. Among authors: zizza p. J Am Chem Soc. 2014 Dec 3;136(48):16708-11. doi: 10.1021/ja5080773. Epub 2014 Nov 19. J Am Chem Soc. 2014. PMID: 25393214
Identification of novel interactors of human telomeric G-quadruplex DNA.
Pagano B, Margarucci L, Zizza P, Amato J, Iaccarino N, Cassiano C, Salvati E, Novellino E, Biroccio A, Casapullo A, Randazzo A. Pagano B, et al. Among authors: zizza p. Chem Commun (Camb). 2015 Feb 18;51(14):2964-7. doi: 10.1039/c4cc07231f. Chem Commun (Camb). 2015. PMID: 25594748
A basal level of DNA damage and telomere deprotection increases the sensitivity of cancer cells to G-quadruplex interactive compounds.
Salvati E, Rizzo A, Iachettini S, Zizza P, Cingolani C, D'Angelo C, Porru M, Mondello C, Aiello A, Farsetti A, Gilson E, Leonetti C, Biroccio A. Salvati E, et al. Among authors: zizza p. Nucleic Acids Res. 2015 Feb 18;43(3):1759-69. doi: 10.1093/nar/gkv006. Epub 2015 Jan 23. Nucleic Acids Res. 2015. PMID: 25618850 Free PMC article.
44 results