Zisterer DM - Search Results

1

Combretazet-3 a novel synthetic cis-stable combretastatin A-4-azetidinone hybrid with enhanced stability and therapeutic efficacy in colon cancer.

Greene LM, Wang S, O'Boyle NM, Bright SA, Reid JE, Kelly P, Meegan MJ, Zisterer DM. Greene LM, et al. Among authors: zisterer dm. Oncol Rep. 2013 Jun;29(6):2451-8. doi: 10.3892/or.2013.2379. Epub 2013 Apr 3. Oncol Rep. 2013. PMID: 23564200

2

Flexible estrogen receptor modulators: design, synthesis, and antagonistic effects in human MCF-7 breast cancer cells.

Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM. Meegan MJ, et al. Among authors: zisterer dm. J Med Chem. 2001 Mar 29;44(7):1072-84. doi: 10.1021/jm001119l. J Med Chem. 2001. PMID: 11297454

3

Ethyl side-chain modifications in novel flexible antiestrogens--design, synthesis and biological efficacy in assay against the MCF-7 breast tumor cell line.

Meegan MJ, Hughes RB, Lloyd DG, Williams DC, Zisterer DM. Meegan MJ, et al. Among authors: zisterer dm. Anticancer Drug Des. 2001 Feb;16(1):57-69. Anticancer Drug Des. 2001. PMID: 11762645

4

Selective induction of apoptosis by the pyrrolo-1,5-benzoxazepine 7-[[dimethylcarbamoyl]oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia cells occurs via the c-Jun NH2-terminal kinase-dependent phosphorylation and inactivation of Bcl-2 and Bcl-XL.

Mc Gee MM, Greene LM, Ledwidge S, Campiani G, Nacci V, Lawler M, Williams DC, Zisterer DM. Mc Gee MM, et al. Among authors: zisterer dm. J Pharmacol Exp Ther. 2004 Sep;310(3):1084-95. doi: 10.1124/jpet.104.067561. Epub 2004 May 13. J Pharmacol Exp Ther. 2004. PMID: 15143129

5

Benzoxepin-derived estrogen receptor modulators: a novel molecular scaffold for the estrogen receptor.

Lloyd DG, Hughes RB, Zisterer DM, Williams DC, Fattorusso C, Catalanotti B, Campiani G, Meegan MJ. Lloyd DG, et al. Among authors: zisterer dm. J Med Chem. 2004 Nov 4;47(23):5612-5. doi: 10.1021/jm0495834. J Med Chem. 2004. PMID: 15509159

6

The pyrrolo-1,5-benzoxazepine, PBOX-6, inhibits the growth of breast cancer cells in vitro independent of estrogen receptor status and inhibits breast tumour growth in vivo.

Greene LM, Fleeton M, Mulligan J, Gowda C, Sheahan BJ, Atkins GJ, Campiani G, Nacci V, Lawler M, Williams DC, Zisterer DM. Greene LM, et al. Among authors: zisterer dm. Oncol Rep. 2005 Nov;14(5):1357-63. Oncol Rep. 2005. PMID: 16211309

7

Identification of tubulin as the molecular target of proapoptotic pyrrolo-1,5-benzoxazepines.

Mulligan JM, Greene LM, Cloonan S, Mc Gee MM, Onnis V, Campiani G, Fattorusso C, Lawler M, Williams DC, Zisterer DM. Mulligan JM, et al. Among authors: zisterer dm. Mol Pharmacol. 2006 Jul;70(1):60-70. doi: 10.1124/mol.105.021204. Epub 2006 Mar 29. Mol Pharmacol. 2006. PMID: 16571652

8

Antiestrogenically active 2-benzyl-1,1-diarylbut-2-enes: synthesis, structure-activity relationships and molecular modeling study for flexible estrogen receptor antagonists.

Lloyd DG, Smith HM, O'Sullivan T, Knox AS, Zisterer DM, Meegan MJ. Lloyd DG, et al. Among authors: zisterer dm. Med Chem. 2006 Mar;2(2):147-68. doi: 10.2174/157340606776056142. Med Chem. 2006. PMID: 16787364

9

Synthesis, structure-activity relationships and antagonistic effects in human MCF-7 breast cancer cells of flexible estrogen receptor modulators.

Lloyd DG, Smith HM, O'Sullivan T, Zisterer DM, Meegan MJ. Lloyd DG, et al. Among authors: zisterer dm. Med Chem. 2005 Jul;1(4):335-53. doi: 10.2174/1573406054368666. Med Chem. 2005. PMID: 16789891

10

STI-571 (imatinib mesylate) enhances the apoptotic efficacy of pyrrolo-1,5-benzoxazepine-6, a novel microtubule-targeting agent, in both STI-571-sensitive and -resistant Bcr-Abl-positive human chronic myeloid leukemia cells.

Greene LM, Kelly L, Onnis V, Campiani G, Lawler M, Williams DC, Zisterer DM. Greene LM, et al. Among authors: zisterer dm. J Pharmacol Exp Ther. 2007 Apr;321(1):288-97. doi: 10.1124/jpet.106.116640. Epub 2007 Jan 3. J Pharmacol Exp Ther. 2007. PMID: 17202400

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